Cholestabyl review

Cholestabyl is a type of bile acid-binding resin that helps the liver to produce more bile acid. When the liver produces more bile acid, it helps the body in eliminating more cholesterol and lowering cholesterol levels.


Cholestabyl is recommended for individuals suffering from primary hypercholesterolemia, or those who have high cholesterol. It is advised that Cholestabyl is taken to complement an exercise program and a healthy diet consisting of low fat and low-cholesterol foods. Cholestabyl is marketed under the brand name Colestid.


Cholestabyl is administered orally. The usual dosage is 1-2 times a day. Users should take Cholestabyl with a large glass of water. In case the physician prescribes dosage of more than 1 tablet, never swallow both pills at once. Instead, take them one after another. Never chew or crush the pills.

The dosage for Cholestabyl is usually based on the patient's medical condition. Physicians usually increase the dosage once the patient responds well to the treatment. It usually takes from 2 weeks to several months before Cholestabyl effectively lowers the cholesterol level in the body.

For best results, it is recommended that patients follow the prescribed dosage. It helps if patients take Cholestabyl at the same time every day so they will not miss a dosage.

Patients should also take other medications an hour before or 4 hours after they have taken Cholestabyl. They should never take 2 doses of Cholestabyl to make up for a missed dosage.


One of the most common side effects of Cholestabyl is costiveness. It is advised that patients drink lots of water, at least 8 glasses each day, to prevent costiveness.

Other side effects of Cholestabyl include indigestion, pain in the abdomen, upset stomach, diarrhoea, heartburn, nausea, irritation of the hemorrhoids, and vomiting. If any of these side effects continue or worsen, patients should immediately notify their physicians.

Some of the more unlikely but severe side effects include muscle aches, pain and stiffness in the joints, unexplained bruising or bleeding, headache, and loss of appetite.

It is very rare that users of Cholestabyl suffer from serious allergic reactions. Patients may however experience swelling, itching, rashes, difficulty in breathing, and dizziness, which indicate an allergic reaction to the medication.


Patients should inform their physicians of any atopy to Cholestabyl or any other medication. They should also inform their physician if they have an intestinal obstruction.

A patient's medical history should be noted before prescribing Cholestabyl. Swallowing problems, a history of major intestinal procedure, treatment with thyroid medication, costiveness problems, liver troubles, and certain bleeding troubles such as hypoprothrombinemia should be taken into account.

It has not been established if taking Cholestabyl can be passed onto infants through breast milk.


Certain medications whether prescription or non-prescription, may also interfere with Cholestabyl. Patients should inform their physician if they are taking other medications like propranolol, hydrochlorothiazide, chorothiazide, gefibrozil, digoxin, oral phosphate supplements, hydrocortisone, and tetracycline.

Cholestabyl may interfere with the body's absorption of these medications if they are taken closely with the dosage of Cholestabyl.

Cholestabyl has the following structural formula:

Chemical structure of cholestabyl

 Molecular formula of cholestabyl is C11H28ClN5O
 Chemical IUPAC Name is N'-(2-aminoethyl)-N-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine; 2-(chloromethyl)oxirane
 Molecular weight is 281.826 g/mol

Generic name: Colestipol

Brand name(s): Colestid, Colestipolum, Flavored Colestid

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