Cipril review

Patients with gastrointestinal problems can now find relief with the development of Cipril. The effectiveness of the medication has shown to be quite useful for many for years to come. It does have a number of reactions and effects that should be watched for.

Cipril is the generic name of the gastrointestinal stimulant used for the treatment of nighttime pyrosis, bowel constipation and GERD or gastroesophageal reflux disease. It is also known by its brand name Propulsid and Prepulsid. Patients who do not respond well to other forms of treatment and therapies are given Cipril.

Cipril comes in a liquid and tablets that should be taken orally. Although the medication has shown potency in treating bowel disorders, doctors are discouraged from immediately giving the medication unless other alternatives are ineffective. It was approved by the Food and Drug Administration in 1993 but later was withdrawn in several areas or had limited indications due to reports of arrhythmia and cardiac irregularities.

This medication is also used in treating megaesophagus and feline megacolon. However, it should not be used for other alternative uses unknown to doctors. It is also useful in treating nausea stemming from motility problems. Cipril is related to metoclopramide for their similar effects but the latter is more potent in treating neurological reactions.

A number of side effects can result from use of the medication and should be cautiously watched out for. Patients should stop the medication immediately and report to their doctor if any of these symptoms are noticed: fainting, allergic reactions, cardiac arrhythmia, chest pain, difficulty breathing and vision changes. Less serious side effects include abdominal pain, diarrhea, constipation, nausea, urinary frequency, upset stomach, rhinorrhea, cough and cephalalgia. Patients may resume taking Cipril but the symptoms should be reported to your doctor. Cipril overdose is also possible and symptoms include diarrhea, vomiting, flatulence, tremor, seizure, weakness and nausea. Seek immediate medical attention if you notice any of these symptoms.

Pregnant women and nursing mothers should consult their doctor before taking the medication. Patients trying to become pregnant should not take the medication since it can reduce fertility. Cipril may interact with medications like cimetidine, ranitidine, antifungals like ketoconazole, antihistamines, psychoactive medications, heart medications and benzodiazepines. If there is intestinal perforation or obstruction, the medication is contraindicated. Pomegranate juice, tobacco, alcohol, grapefruit juice and red wine are known to reduce the effects and absorption of the medication in the body. Other contraindications include patients with a history of heart and arterial disease.

Cipril is a parasympathomimetic medication that acts as an agonist for serotonin 5-HT4 receptors. Once the receptors are stimulated, acetylcholine levels will rise in the enteric nervous system, improving the gastroesophageal condition. The esophageal sphincter also improves with effective gastric emptying.

A clinical trial involving 18 patients suffering from GERD were treated with Cipril and metoclopramide. The group was divided into two wherein the first batch was given Cipril while the second took metoclopramide. After 7 days, both batches exhibited improvement in gastroesophageal condition. The first batch did experience nausea for 1 to 2 days but the second batch reported experiencing moderate neurological side effects.

Cipril is a prescription medication and should only be bought from authorized clinics and pharmacies. Be sure to verify any online pharmacy before purchasing to guarantee authenticity of products.

Cipril can be given up to three times daily. Never take more than the recommended dosage. The medication should be stored at room temperature free from heat, moisture and children's reach. Watch out for symptoms of overdose and immediately call for help if anything results. Doctors require laboratory assessment to ensure the safety of the patient with the medication.

Cipril has the following structural formula:

Chemical structure of cipril

• Molecular formula of cipril is C23H29ClFN3O4
• Chemical IUPAC Name is 4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
• Molecular weight is 465.9455 g/mol
Cipril available : 5mg tablets, 10mg tablets

Generic name: Cisapride

Brand name(s): Acenalin, Alimix, Enteropride, Kinestase, Prepulsid, Pridesia, Propulsid, Propulsin, Risamal, Syspride

  Your Cipril review