is a chemotherapy medicament used in the treatment of various cancers including sarcomas, carcinomas, germ cell tumors and lymphomas. Cisplatine is distributed in the US under the brand names Platinol and Platinol-AQ
The dosage and length of treatment depend on the type of cancer
and the response of the patient to the chemotherapy. This medicament is given through infusion with a fine tube inserted through the vein at the back of the hand
or near the collarbone. The process can last eight hours or more and is only done in a hospital.
Some patients may experience minor side effects while others experience serious side effects. The most common side effect is wamble or sickness
, usually occurring a few hours after the medicament has been administered. When this happens, your doctor will prescribe anti-sickness medicines to reduce this side effect.
There are cases where the medicament affects the kidney
and may even cause permanent damage if not immediately attended to by a doctor. Your doctor may conduct blood
tests prior to each treatment to determine if it is safe to continue with the medicament. You will be given fluid intravenously to ensure that your kidneys
are functioning well.
Some patients may also feel numbness in the hands or feet but this will disappear a few months after treatment. The medicament may affect your hearing and taste sensation.
Cisplatine reduces the immune system, making the body prone to infections because the medicament decreases the production capability of the bone
marrow in producing white blood cells
. It can also cause Anemia
making the patient tired and weak.
If you experience or notice something unusual while undergoing treatment, it is important to inform your doctor immediately.
Before undergoing treatment or chemotherapy sessions, tell your doctor of all the medicaments you are taking. This includes prescribed and non-prescribed medicaments. This is to help your doctor determine if you are taking medicaments that might interact with Cisplatine that may cause complications or harm your health.
Something to consider before taking Cisplatine is fertility since this medicament affects the fertility of both men and women. Discuss with your doctor the benefits and risks involved when using this medicament.
While undergoing treatment, avoid becoming pregnant or fathering a child because this medicament may cause harm to the baby. Use an effective birth control
while undergoing treatment. Discuss your options with your doctor to determine the best methods to use.
Make sure to follow your chemotherapy schedule as well as the laboratory tests and medical exams required. This will allow your doctor to evaluate the progress of your treatment as well as to immediately identify any problems that may occur. It will also help your doctor determine if there are any adjustments that need to be made to your present dosage.
Cisplatine has the following structural formula:
• Molecular formula of cisplatine is Cl2H4N2Pt
• Molecular weight is 298.029 g/mol
• Cisplatine available : 50ml injection, 100ml injection and 200ml injection