Clafen review

Clafen is a medication used for the interposition of various types of cancer. Aside from being a cytotoxic medication, Clafen is an immunosuppressive since it can suppress the immune system.


Clafen is marketed under the brand name Cytoxan. It is uncommitted in tablet form as well as a powder used for intravenous injection. It is prescribed to individuals who are suffering from certain types of cancer such as ovarian, breast, and leukemia. It is also known to cure nephritic syndrome, an ailment of the kidneys among children.


The initial dosage of Clafen is at least 40 mg injected in a stretch of 3 to 5 days divided in various doses. The usual dosage for oral use is 1 to 5 mg/kg per day. The dosage is then adjusted depending on the tumor's response to the medication and its side effects.

Clafen should be taken as prescribed by your doctor. While using Clafen, affected roles should drink more water and urinate more frequently. This should help the kidneys in removing the medication from the system and lower the chances of occurrence of side effects.

Patients should not stop using Clafen until the prescribed schedule is complete, even if the affected role experiences nausea or vomiting.

This medication usually works a month or two before producing positive results. The effects also depend on the disease being treated.


One of the most common side effects is nausea. Doctors usually prescribe another medication to reduce this side effect.

Users may also experience bleeding and inflammation of the bladder wall, or haemorrhagic cystitis characterized by blood in the urine. To reduce the chances of this side effect, affected roles are advised to drink more water, preferably up to 10 glasses a day.

This medication can also have an effect on the blood count of the affected role. It can also result in hair loss, irregular menstrual periods, and mouth ulcers. In case a affected role develops these symptoms after using Clafen, he or she should immediately inform their doctor.

Patients who come into close contact with a person with chicken pox are advised to stop using Clafen and immediately consult their doctor. This case usually requires a special, antiviral interposition since chicken pox can be severe among people who are undergoing interposition with Clafen.

Since Clafen may affect the bladder and the blood, doctors may have to arrange for a blood and urine examination before allowing the affected role to start interposition with Clafen. Regular examinations are also required while the affected role takes Clafen. Patients should not take Clafen unless they are undergoing regular blood and urine examinations.


Certain medications may interact negatively with other medications. Patients should make it a point to inform their physicians if they are beginning to take new medications while taking Clafen.

Taking Clafen may lead to a decrease in fertility among women and men; so young users are advised to use this medication with caution.


Pregnant women should never take this medication. Clafen may also be passed on to infants so breastfeeding mothers should not take this medication.

Clafen has the following structural formula:

Chemical structure of clafen

 Molecular formula of clafen is C7H15C12N2O2P·H2O
 Chemical IUPAC Name is 2-[bis(2-chloroethyl)amino] tetrahydro-2H-13,2-oxazaphosphorine 2-oxide monohydrate
 Molecular weight is 279.1 g/mol
 Clafen available : 25mg tablets, 50mg tablets

Generic name: Cyclophosphamide

Brand name(s): Claphene, Cyclophosphamid, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphoramide, Cyclostin, Cyklofosfamid, Cytophosphan, Cytoxan, Endoxan, Endoxan R, Endoxana, Endoxanal, Endoxane, Enduxan, Genoxal, Hexadrin, Lyophilized Cytoxan, Mitoxan, Neosar, Procytox, Semdoxan, Sendoxan, Senduxan, Zyklophosphamid

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