Clobazam review

Clobazam is part of a group of drugs called benzodiazepines. It is specifically prescribed for the treatment of seizure disorders, which are caused by the increased electrical movement in the brain.

Those who are suffering from seizure may take Clobazam. The drug can also be used to complement other anti-seizure drugs when additional treatment for seizure control is required. It can be taken by adults and children.

Adults are required to take at least 5 milligrams of Clobazam daily, with a maximum of 80 milligrams dosage per day. These can be taken in 1-2 dosages, and can be taken on an empty stomach. For children up to 16 years, the dosage should be initially at 5 milligrams, with increment of up to 40 milligrams daily. For children who are under 2 years of age, the initial dosage depends on the body weight. Those who have decreased kidney and liver function are recommended to have lessened dosage.

Patients should see to it that they follow the regular scheduled as advised by a physician. In case they miss a dose, take it immediately. If it is about time for the next dose, just skip the dose and proceed to the next dosage. Patients should not take two dosages to make up for a missed dose.

Like most drugs, Clobazam can cause side effects. Patients should immediately inform their physicians in case they notice side effects from the use of Clobazam.

Some of the more common side effects of Clobazam are unsteadiness, dizziness, slurred speech and drowsiness. Rare side effects include pain in the stomach or abdomen, blurred vision, diarrhea, constipation, headache, muscle spam, and vomiting. Patients may also experience difficulty in urinating, trembling, and unusual gain in weight.

Other side effects include irregular heartbeat, anxiety, depression, agitation, convulsions, muscle weakness, low blood pressure, and changes in behavior (for example, sudden aggressiveness).

Those who have allergy to benzodiazepines should not take Clobazam. Likewise, patients suffering from myasthenia gravis, serious liver impairment, and closed-angle glaucoma are discouraged from taking Clobazam. Pregnant women as well as those breastfeeding are also discouraged from taking this medication.

Clobazam is also not recommended to those suffering from psychosis. Likewise, the drug should be taken with caution by the elderly as well as debilitated individuals. Those suffering from organic brain problems like dementia and breathing disorders like asthma are also cautioned into taking this medication.

The medication may also affect the physical coordination and mental alertness of individuals, so those who drive or operate dangerous machineries may not be recommended to take Clobazam. Doctors may first determine the effects of Clobazam before prescribing it to these types of individuals.

Clobazam has also been proven to be habit-forming. Those who suddenly stopped taking Clobazam have shown withdrawal symptoms like seizures, vomiting, headache, nervousness, sleep problems, diarrhea, abdominal cramps, extreme anxiety, and memory impairment. Other symptoms may also include irritability, tension, and restlessness. Patients are advised to gradually reduce their intake of Clobazam to prevent these symptoms.

Clobazam has the following structural formula:

Chemical structure of clobazam

• Molecular weight is 300.7396 g/mol
Clobazam available : 10mg tablets

Brand name(s): Chlorepin, Clorepin, Frisium, Mystan, Urbadan, Urbanyl

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