Clonidinum review

Clonidinum is an antihypertensive medicament that can help patients deal with psychological bouts and is effective in children with ADHD, but needs to be taken properly to maintain efficiency and safety.

Clonidinum acts as an a2 adrenergic agonist. Generally used to treat hypertension by stimulating brain receptors to relax blood vessels in the body, it is also used to treat Tourette's syndrome, neuropathic pain, sleep hyperhydrosis and opioid detoxification. Clonidinum can be used with stimulants to treat ADHD. Its effects on moderate ADHD-associated oppositional and impulsive behavior are helpful in managing tics.

Clonidinum is also known by the brand names Catapres and Dixarit and comes in a tablet, an injectable via epidural and transdermal patches. Parasympathetic activity results through central nervous system actions. A patient's heart rate can significantly decrease with continued use of the medicament. Other uses of Clonidinum include treating migraine headaches, menopausal hot flashes, alcohol withdrawal symptoms, smoking cessation symptoms and ulcerative colitis.

The medicament can result in side effects that are mild, moderate or severe. Your physician should be contacted immediately if any of these symptoms become severe: dry mouth, dizziness, drowsiness, fatigability, headache, constipation, nervousness, decreased libido, upset stomach, rash and vomiting. Other serious side effects include fainting, slow or rapid heartbeat, arrhythmia, swollen feet or ankles and allergic symptoms like facial and lips skin edema, breathing difficulty and hives. Orthostatic hypotension, xerostomia and tolerance to Clonidinum may result.

Special precautions are taken with pregnant women and nursing mothers. Patients about to undergo surgery, including dental procedures, should inform their physician to avoid bleeding complications. Patients allergic to the medicament should not take it and those with a history of kidney disease, heart attach, stroke and coronary artery disease should inform their physician first before taking Clonidinum. The medicament may cause adverse effects if the patient is also taking beta blockers, sleeping pills, and a number of supplements, vitamins and herbal medicines.

Clonidinum acts as an a-adrenergic receptor agonist and has more affinity for a2 compared to a1. Brain receptors are selectively stimulated by the medicament. These receptors are responsible for monitoring catecholamine levels in the blood. This stimulation causes the receptors to think that levels of catecholamine are higher than they are. The result is a reduction of catecholamine production and blood levels through relaxation and widening of blood vessels.

A survey of 35 children with FXS who were treated with Clonidinum showed significant improvement in sleep disturbances, motor tics and hyperactivity. 63% of parents reported overall improvement in their child's condition, 20% reported minor improvement, 11% reported their child's condition became worse while 6% reported no noticeable effect. There were a number of exacerbated symptoms as well, including mood condition and sleep disturbances.

Clonidinum is a prescription medicament and should only be purchased from legitimate and verified pharmacies and physicians' clinics. The pills and patches are also available online but consumers should check the source and manufacturer first to ensure freshness and authenticity of the products.

Patients should watch out for symptoms of Clonidinum overdose such as lethargy, lightheadedness, vomiting and drowsiness. The dosage should be taken as prescribed by your physician. The medicament should not be stopped abruptly even if the patient's condition becomes better. The medicament may need to be taken for life by those patients suffering from chronic hypertension for maintenance. Store the medicament at room temperature away from sunlight, heat and moisture.

Clonidinum has the following structural formula:

Chemical structure of clonidinum

 Molecular formula of clonidinum is C9H9Cl2N3
 Chemical IUPAC Name is N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
 Molecular weight is 230.093 g/mol
 Clonidinum available : 0.1mg tablets, 0.2mg tablets, 0.3mg tablets

Generic name: Clonidine

Brand name(s): Adesipress, Catapres, Catapresan, Catapressan, Catarpres, Catarpresan, Chlornidinum, Clonidin, Clonistada, Combipres, Dixarit, Duraclon, Duraclont, Ipotensium, Isoglaucon

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