is used for the treatment of infertility among female patients. It stimulates increased hormones
vital to the growth and release of mature eggs for ovulation.
Clostilbegyt is available in pill form and marketed under the brand names Clomin, Milophene
, and Ikaclomin
Patients having difficulties becoming pregnant may take Clostilbegyt. It may be used in conjunction with a medicine called Metformin
to help patients ovulate and become pregnant.
Studies reveal that 70 % of patients who used Clostilbegyt were able to ovulate, a good majority of them during the first months of treatment. Of that population, 15-50% became pregnant.
Patients are prescribed 50 milligrams of Clostilbegyt for 5 days beginning on the fifth day of their menstrual cycle
. In case ovulation does not occur, dose can be increased to 100 milligrams for 5 days the month after the previous dose. It is not advised that patients take Clostilbegyt after 6 treatment cycles.
Follow the dosing schedule to get the best results. Patients should not take the medication for longer than the physician prescribed. In case of a missed dose, patients should immediately inform their physician to determine the next steps. It is not recommended that patients take double doses to resume their dosing schedule.
For best results, physicians may look into some factors, including the body temperature of the patient and ovulation tests prior to prescribing Clostilbegyt.
Side effects include upset stomach
, hot flashes, pelvic fullness, headache
tenderness, or dizziness
. If these symptoms persist, patients should immediately notify their physicians. In general, the chances of a patient experiencing these side effects are low.
Changes in the patient's vision, such as seeing flashes, is another possible side effect while taking Clostilbegyt. This is more common if the patient is exposed to intense lighting. If a patient does experience this side effect, it may go away after a couple of days after treatment. If it does not go away on it's own, consult your doctor.
Serious side effects include vaginal bleeding and changes in moods. Some patients may experience severe pain or swelling
in the pelvic area, diarrhea
, difficulty in breathing, chest pain
, irregular heartbeat
, and swelling of the legs
Before taking Clostilbegyt, women should inform their physician about any history of allergies
to medications. Patients should also consult their physician about their conditions such as liver
illness, vaginal bleeding, uncontrolled thyroid, and pituitary tumor before agreeing to use Clostilbegyt.
There have been cases where the use of Clostilbegyt resulted in the patient having multiple births like twins and triplets.
Women are advised against engaging in activities that require mental alertness such as driving since Clostilbegyt can make a person dizzy or suffer from blurred vision.
Patients should tell their physician or pharmacist about all the prescription medicines they are using before taking Clostilbegyt.
Clostilbegyt has the following structural formula:
• Molecular formula of clostilbegyt is C26H28ClNO
• Chemical IUPAC Name is 2-[4-[(Z)-2-chloro-1,2-di(phenyl)ethenyl]phenoxy]-N,N-diethylethanamine
• Molecular weight is 405.9596 g/mol
• Clostilbegyt available : 50mg tablets