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ADVERTISING

Cloxacilina


Cloxacilina

Cloxacilina review



buy Cloxacilina Buy Cloxacilina
Cloxacilina is one effective antibiotic promising good results without the risk of serious side effects. Like other medications, there are interactions and affects to watch for to ensure that patients stay healthy and safe.

CLOXACILLINA ACTION

Cloxacilina is the generic name of the semisynthetic antibiotic belonging in the same class as penicillin. It is also available as the brand names Cloxapen, Orbenin and Tegopen. The medication is primarily used to fight staphylococci bacteria that produce beta-lactamase. It has weaker antibacterial actions compared to benzylpenicillin and is less potent, causing fewer toxic reactions.

Cloxacilina is highly useful in the interposition of staphylococcus infections. It is available in tablets and suspension. The medication is for the interposition of respiratory tract infection, urinary tract infection, bone and joint infection and skin infection. Even infections in the heart and lungs can be treated with Cloxacilina and in very severe cases the medication may be administered intravenously.

CLOXACILLINA SIDE EFFECTS

Many side effects are associated with concurrent use of Cloxacilina such as nausea, vomiting, diarrhea, stomach ache, white patches on the tongue, vaginal itching or discharge, black tongue and sore mouth. Serious side effects that need immediate medical attention include shortness of breath, toughy breathing and facial or lip swelling from anaphylactic reactions, seizure, bruising, bleeding, water diarrhea, abdominal cramping, tingling or loss of sensation in the extremities, confusion coma and irritability. Cloxacilina overdosage can also occur and manifest through symptoms like hallucination, encephalopathy, confusion, electrolyte imbalance and skin rash.

CLOXACILLINA DURING PREGNANCY

Individuals with a history of kidney disease, gastrointestinal or stomach problems, infectious mononucleosis and heart disease should consult their doctor first before taking the medication. Pregnant women and breastfeeding mothers need to be cautious as well. Diabetic patients may experience false positive results when taking glucose urine tests while on the medication.

CLOXACILLINA INTERACTIONS

Cloxacilina may interact with various substances as well so consume alcohol moderately and ask a physician first before taking medications like erythromycin, tetracycline, birth control pills, allopurinol and methotrexate. Those with known hypersensitivity reactions to the medication should not take it.

CLOXACILLINA PRECAUTIONS

The medication is absorbed then distributed to the kidneys, liver, bone, bile, pleural fluid, ascitic fluid and synovial fluid with some amounts into the CSF as well. 90% to 95% of the medication binds to plasma proteins. Its main action is to inhibit bacterial cell wall synthesis by binding to PBPs or penicillin-binding proteins. The result would be inhibition of transpeptidation phase of peptidoglycan synthesis in cell walls of bacteria, which prevents biosynthesis of cell walls. Bacteria will then be engulfed, swallowed or destroyed as cell wall formation is disrupted.

CLOXACILLINA DOSAGE

A clinical study was conducted involving 18 patients who had skin infection caused by staphylococci. Half of the group was given 250 mg of Cloxacilina every 6 hours for two weeks while the rest were provided with a placebo. After the first week, those on Cloxacilina showed significant improvement in their skin and by the second week, 7 out of 9 were already showing signs of being free from infection like absence of moisture and pus. None of those on placebo showed any improvement while 3 even had exacerbated symptoms like fever.

Cloxacilina is an over-the-counter or OTC medication, which can easily be bought at any apothecary shop, clinic or online drug store. Check the expiration date, manufacturer and address to ensure that products are legitimate and authentic. When buying online, make sure that the source is certified.

Cloxacilina should not be abruptly stopped even if individuals already feel better. Each dosage should be taken with a full glass of water on an empty stomach around 1 hour before or 2 hours after meals. Avoid drinking juice or carbonated drinks with the medication since these can reduce effectiveness.

Cloxacilina has the following structural formula:

Chemical structure of cloxacilina


 Molecular formula of cloxacilina is C19H18ClN3O5S
 Chemical IUPAC Name is 7-[[3-(2-chlorophenyl)-5-methyl-oxazol-4-yl]carbonylamino]-3,3-dimethyl-6-oxo-2-thia-5-azabicyclo[3.2.0]heptane-4-carboxylic acid
 Molecular weight is 435.882 g/mol
 Cloxacilina available : 250mg tablets, 500mg tablets

Generic name: Cloxacillin

Brand name(s): Clossacillina, Cloxacilline, Cloxacillinum, Cloxapen, Dycill, Dynapen, Pathocil, Syntarpen, Tegopen

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