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Cogentine

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Cogentine

Cogentine review





Cogentine, an anticholinergic medicament, is used for treating Parkinsons disease and related conditions such as parkinsonism, dystonia, and akathasia. It is been shown to have an effective and significant therapeutic value in the management of the symptoms of parkinsonism. It counteracts the effects of the neurotransmitter acetylcholine and balances the levels of acetylcholine and dopamine in the body, which can help reduce the symptoms of Parkinson's disease in its early stages. It can also be used to treat movement disorders resulting from the use of other antipsychotic medicament. Doctors have also observed an antihistaminic activity approaching that of pyrilamine maleate.

It is available in 0.5 mg, 1 mg or 2 mg tablets.

This medicament is primarily prescribed for most forms of parkinsonism and movement disorders resulting from the use of antipsychotic medicaments, with the exception of tardive dyskenesia. It can also be a useful part of Parkinson's treatment because it helps reduce symptoms of tremors. Patients with dystonia also benefit from Cogentine since it can relax the sudden contortions of the limbs and torso.

Cogentine is prescribed using the lowest dose possible, with the doctor monitoring the patient's condition as the dose is increased by 0.5mg every 5 to 6 days, up to a maximum dose of 6 mg. The reason is to find the optimal dose for the patient using the least amount of medicine possible.

The doctor will often instruct the patient to take the medicine 2 to 4 times each day along with meals and before bedtime or as a single dose at bedtime. Though the doctor may modify the dose as they see fit based on the patient's condition and their reaction to the medicament.

Cogentine should be taken no less than an hour before taking antacids containing calcium, magnesium or aluminum. Also take this medicament one to two hours before and after taking Cogentine when taking adsorbent diarrhea medicament containing pectin, kaolin or attapulgite as this may affect the body's absorption of Cogentine. If you are taking ketoconazole, do not take Cogentine until two hours after the ketoconazole dose as it may affect the absorption of the keotconazole.

When Cogentine is being taken to counteract side effects caused by another antipsychotic medicament, your doctor may have you take it only as necessary. The doctor may also alter the dose of the other medicaments you are taking. Follow the doctor's prescriptions carefully.

An addiction may arise from the use of this medicament. Do not extend your treatment or increase your dose unless directed to do so by your doctor. Proper halting of treatment will be necessary. In certain cases, an abrupt discontinuing of dose may aggravate certain symptoms so your doctor will design an increasingly lowered dose until you can safely stop taking this medicament when the time is right.

Side effects include dizziness, constipation, nausea, drowsiness, blurred vision or a xerostomia. The side effects may reduce as you become used to the medicament, but if any of these symptoms worsen or persist, consult with your doctor.

Inform your doctor immediately if you experience high fevers, severe stomach pain, difficulty passing urine, weakness or a decrease in sexual ability. If you feel chest pains, dizziness which results in fainting, mood swings or mental disturbances, irregular heartbeats or symptoms of extreme allergic reactions such as rashes, fever or inflammation, seek immediate medical attention.

Before taking this medicament, inform your doctor of your complete medical history, including any existing medical conditions such as heart disease, glaucoma, gastrointestinal disorders such as ulcers and blockage, liver disease, other mental and movement disorders, high blood pressure, or disorders causing difficulty in peeing.

Cogentine may cause drowsiness. Avoid driving or operating machinery while taking this medicament. Also, avoid spending time in poorly ventilated, hot areas as some patients may experience an increase in body temperature.

Cogentine has the following structural formula:

Chemical structure of cogentine


• Molecular formula of cogentine is C21H25NO
• Chemical IUPAC Name is 3-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane
• Molecular weight is 307.429 g/mol
Cogentine available : 0,5mg tablets, 1mg tablets and 2mg tablets

Generic name: Benztropine

Brand name(s): Akitan, Benzatropina, Benzatropine, Benzatropinum, Benztropine mesylate, Benztropinum, Cobrentin, Cogentin, Cogentinol

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