Colimune review

Colimune is a mast cell stabilizer that prevents the release of inflammation-inducing chemicals including histamine used to control various conditions including asthma and allergic conjunctivitis.


Colimune is marketed as sodium cromoglicate and cromolyn sodium. This medication is available as a nasal spray under the brand names Nasalcrom and Rynacrom, which patients with allergic rhinitis can use. Patients with asthma can also buy this medication under the brand name Intal, while those who have allergic conjunctivitis can purchase it under the brand name Crolom, Opticrom, or Optrex. Patients with ulcerative colitis and mastocytosis can purchase this medication under the brand name Gastrocrom.

Colimune has been proven effective in reducing symptoms of food allergies, and in some cases, chronic migraines.


Dosages of Colimune vary based on the condition being treated. For food allergies, Colimune is usually prescribed to adults as 200 mg pills four times a day. The dose is typically 100 mg for children. Dosage may be increased if the medication is not showing results after 2 weeks.

For patients with mastocytis, a 20 milligram dose is usually taken 4 times a day. For patients with allergic conjunctivitis, Colimune is usually administered by instilling 2 drops of a 4% solution spray, taken four times a day.

Asthmatics may use Colimune as a dry powder taking a 20 milligram dose four times a day. For the aerosol, the dose is 10 milligrams taken four times a day. If the condition does not improve, the dose can be increased up to 8 times a day. Dosage can be lowered to 5 milligrams taken 4 times a day after the condition has improved.


Patients taking Colimune may experience side effects including skin rashes, nausea, dizziness, cephalalgia, pain and skin edema in the joints, and unpleasant taste in the mouth. Patients may also aggravate their asthma attacks, or suffer from pulmonary infiltrates. Patients may also experience wheezing, nasal congestion, cough, and throat irritation especially after inhaling the dry powder. For patients using eye drops, there is a risk of stinging and burning in the eyes.

Patients may develop an allergic reaction to Colimune. They are advised to immediately inform a physician if they experience symptoms of allergic reaction including pruritus, rashes, skin edema, difficulty breathing and severe dizziness.


Colimune may interact negatively when taken with other medications. Patients should tell their doctors if they are taking any medications, whether prescription or non-prescription. Patients are also advised not to alter the dose of Colimune without the approval of their doctor or pharmacist.

Patients using Colimune for self-treatment should first clear with their physicians if they are experiencing any of these symptoms: fever, sinus pain, discolored fluid discharged from the nose, and wheezing.


Colimune can affect pregnant women, but the chances are low. Patients should discuss the risks and the benefits of Colimune with their doctor before taking the medication.

Colimune has the following structural formula:

Chemical structure of colimune

 Molecular formula of colimune is C23H16O11
 Chemical IUPAC Name is 5-[3-(2-carboxy-4-oxochromen-6-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylicacid
 Molecular weight is 468.3665 g/mol
 Colimune available : 100mg tablets

Generic name: Cromoglicate

Brand name(s): Aarane, Alercom, Alerion, Allergocrom, Apo-Cromolyn, Crolom, Cromoglycate, Cromolyn, Cromoptic, Cromovet, Fivent, Gastrocrom, Gastrofrenal, Gen-Cromoglycate, Inostral, Intal, Introl, Irtan, Lomudal, Lomupren, Lomusol, Lomuspray, Nalcrom, Nalcron, Nasalcrom, Nasmil, Opticrom, Opticron, Rynacrom, Sofro, Vistacrom, Vividrin

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