is a selective adrenergic receptor blocker belonging to a class of medicaments, which work directly on the heart
circulation. It is mainly used to treat cardiovascular illnesses such as high blood pressure
(high blood pressure), coronary heart illness, arrhythmias (irregular heartbeat), ischemic heart illness (restricted blood supply to the heart), and myocardial infarction
(necrosis of the heart muscle leading to heart attack).
Concor works by blocking the heart's beta-adrenergic receptors, found in the body's sympathetic nervous system. This reduces the heart rate, preventing an abnormal rapid heartbeat, while relaxing the blood vessels
so the heart does not need to pump too hard.
This medication is used to treat patients with congestive heart failure
by reducing the heart muscle's oxygen consumption. It decreases the heart's contraction force while lowering blood pressure, thereby lessens the heart's need for oxygen. When the heart's need for oxygen exceeds the amount supplied to it, heart pain or angina occurs. This makes Concor ideal for the treatment of angina.
This medication can also be used to treat dysautonomia (disorder of the autonomic nervous system), anxiety
, and hyperthyroidism
(an overactive thyroid gland).
Prior to taking Concor, patients should inform their doctor if they are allergic to the medication or to any other medicaments. The doctor should be made aware if the patient is currently taking any prescription or over-the-counter medicaments, including vitamin, mineral or herbal supplements. The doctor will need to alter the Concor dosage for patients taking calcium
channel blockers like diltiazem
, or guanethidine. Patients taking this medication should not be taking medicaments indicated for irregular heartbeat
, other beta blockers like reserpine, and other contraindicated medicaments such as rifampin
. In these cases close monitoring during Concor therapy is needed.
The doctor will also need to know if the patient has asthma
or other bronchial illnesses; a slow heart rate; a history of heart failure; any existing liver
or heart illness; diabetes; allergies; circulation disorders, or hyperthyroidism. Concor use is contraindicated for these ailments.
The FDA has classified Concor in pregnancy category C, which means it is not known whether the medication can harm an unborn child. Female patients need to inform their doctor if they are pregnant, plan to become pregnant, or become pregnant during the course of treatment. This holds true for breastfeeding patients, as well, since Concor can be secreted into breastmilk and may harm a nursing infant.
Patients also need to disclose their existing Concor therapy prior to any type of surgery, including dental procedures. Concor medication will have to be temporarily ceased, under medical supervision, before undergoing a surgical procedure.
As Concor can cause drowsiness and reduce alertness, patients are advised not to drive a vehicle or operate any kind of machinery while on this medication. Drinking alcoholic beverages may also exacerbate the effect of dizziness
that Concor may cause.
Concor may cause side effects that are mild and easily tolerated. In rare instances, it may result in cephalalgias, nausea
, abdominal cramping, diarrhea
, impotence, slow heart rate, unexplained weight gain, low blood pressure, numbness and tingling, sore throat, clamminess and swelling
of the hands and feet, fainting, and wheezing or shortness of breath. If these symptoms continue, patients are advised to consult their doctor immediately.
should inform their doctor if they are taking Concor, as the medication can alter the results of blood tests for diabetes
, particularly that for hypoglycemia
, or low blood sugar.
Distributed under the brand names Concor, Zebeta
, Concore and Monocor
, it is available by prescription in 5mg and 10mg pink, heart-shaped, film-coated tablets. Concor should be taken orally according to the doctor's directions, once daily with water, at the same time each day. The doctor may also prescribe a low-salt diet to complement treatment.
Because Concor may only form part of a comprehensive treatment program for high blood pressure, it cannot get rid of the illness altogether. Patients are encouraged to stick to a healthy diet, regular exercise and their prescribed medication to control high blood pressure.
Concor is considered a preventive maintenance medication that a patient may need to take for the rest of their lives, even in the absence of hypertensive symptoms. Suddenly stopping Concor therapy without prior medical advice may cause the patient's condition to worsen.
Concor has the following structural formula:
• Molecular formula of concor is C18H31NO4
• Chemical IUPAC Name is 1-[4-[2-(1-methylethoxy)ethoxymethyl]phenoxy]-3-(1-methylethylamino)propan-2-ol
• Molecular weight is 325.443 g/mol
• Concor available : 5mg tablets, 10mg tablets