Cosmegen review

Cosmegen is a medication used in the treatment of various types of cancer such as testicular and sarcomas. It belongs to a group of cancer-fighting medications called antibiotics that stop the growth of cancer cells in the body.

Cosmegen is also available under the brand names Act-D and Actinomycin D. It is commonly prescribed to children, although adults may also be prescribed this medication. Cosmegen is for the treatment of cancers of the soft tissue and bones particularly tendons and muscles, tumors in the womb, and cancer of the testicles.

Cosmegen is injected in a vein for over 15 minutes. Patients are usually given a medicine prior to the administration of Cosmegen to stop any vomiting or wamble once the medication is administered.


The dosage of Cosmegen depends on the affected role's size, blood count, condition and the cancer being treated. Blood counts of affected roles are taken before treatment of Cosmegen. In case results of lab work indicate unsafe conditions, the treatment of Cosmegen will be delayed.

It is usual for affected roles to take Cosmegen with other chemotherapy dugs.


Cosmegen can decrease the amount of white blood cells in the body for weeks after the administration of the medication. This can increase the affected role's risk of infection. Patients should immediately inform their doctors if they notice symptoms of infection like high pyrexia, pain when urinating, chills, or coughs.

Cosmegen can lower the platelet count of the affected role a few weeks after being used, increasing the affected role's risk of bleeding. Patients should notify their physician if they experience unexplained bleeding like nosebleeds, tarry stools, or bleeding gums.

There is also a risk that Cosmegen will decrease the amount of red blood cells in the body. Known as anemia, decreased red blood cell count results in difficulty in breathing, and exhaustion. Doctors may prescribe additional medicines to prevent this condition. Alternatively, affected roles may need to have a blood transfusion.

Patients should not have any vaccinations while taking this medication without the approval of their physician. Cosmegen can affect a affected role's immune system, which can alter the effectiveness of vaccinations. Worse, this can also lead to severe infections.


Patients may also feel sick after taking Cosmegen. Doctors usually prescribed anti-wamble medications to treat wamble and vomiting.

Cosmegen can also result in rapid hair loss. However, this is a temporary side effect and the hair normally grows back after the treatment period.

Patients should inform their doctor of their medical history, especially if they have had liver, kidney, heart illnesss, diabetes, heart failure, gout, kidney stones, and infections. These conditions may require the dosage and timing of Cosmegen to be changed accordingly.

Those who have been treated with radiation are usually given decreased dosages of Cosmegen.


This medication can also have an effect on the fertility of its users. It can also cause birth defects, especially if the mother took Cosmegen during pregnancy or conception. Those who are taking Cosmegen should use birth control to lessen risks of conception.

Cosmegen has the following structural formula:

Chemical structure of cosmegen

 Molecular formula of cosmegen is C62H86N12O16
 Chemical IUPAC Name is 8-amino-N-(2-amino-4,6-dimethyl-3-oxo-phenoxazin-1-yl)carbonyl-N'-[8-amino-4,6-dimethyl-7-oxo-9-[[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]carbamoyl]phenoxazin-1-yl]carbonyl-4,6-dimethyl-7-oxo-N,N'-bis[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]-1,9-bis[[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]carbamoyl]phenoxazine-1,9-dicarboxamide
 Molecular weight is 1255.42 g/mol
 Cosmegen available : 0,5mg injection

Generic name: Dactinomycin

Brand name(s): Dactinomicina, Dactinomycine, Dactinomycinum, Lyovac Cosmegen, Meractinomycin, Oncostatin K, Oxamide

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