Cyclostin review

Cyclostin, a cytotoxic medication and an immunosuppressive (it suppresses the immune system), is used to treat various types of cancer.

Cyclostin is uncommitted under the brand name Cytoxan and comes in tablet form or a powder used for intravenous injection. It is for affected roles with certain types of cancer such as ovarian, breast, and leukemia and is also known to cure nephritic syndrome, an ailment of the kidneys among children.


The initial dose of Cyclostin is a minimum 40 mg injected over 3 to 5 days divided into several doses. The standard dose for oral use is 1 to 5 mg/kg per day. It is then adjusted, if necessary, based on the tumor's response to the medication and the side effects.


Cyclostin is to be taken as prescribed by your healthcare professional. While taking this medication, affected roles should drink more water, which will cause them to urinate more frequently. This will help the kidneys remove the medication from the affected role's system and lower the possibility of side effects.

Patients should not stop taking Cyclostin until the prescribed period is over, even if the affected role experiences nausea or vomiting.

This medication usually needs to be taken for a month, sometimes two, before seeing positive results. The results also depend heavily on the illness being treated.


The most common side effect is nausea. Due to this, healthcare professionals usually prescribe another medication to reduce this symptom.

Patients may experience bleeding and inflammation of the bladder wall, or haemorrhagic cystitis characterized by blood in the urine. To reduce the chances of this, affected roles are advised to drink more water, preferably about 10 glasses a day.

This medication can affect the blood count of the affected role, result in hair loss, irregular menstrual periods, and mouth ulcers. In case a affected role develops any of these symptoms after taking Cyclostin, he or she should immediately inform their healthcare professional.

Patients who come into contact with a person with chicken pox are advised to stop taking Cyclostin and immediately consult their healthcare professional. This usually requires a special antiviral treatment since chicken pox can be severe to affected roles undergoing treatment with Cyclostin.

Since Cyclostin may affect the bladder and the blood, your healthcare professional may arrange for a blood and urine examination before allowing you to start taking Cyclostin. Regular examinations are required while taking Cyclostin. Patients should not take this medication unless they are undergoing regular blood and urine examinations.


Certain medicaments interact negatively with this medication. Patients should inform their healthcare professionals if they start any new medicaments while taking Cyclostin.

Taking Cyclostin may lead to a decrease in fertility. Patients are advised to use this medication with caution.


Pregnant women should not take this medication. Cyclostin may be passed on to infants so breastfeeding mothers should not take this medication.

Cyclostin has the following structural formula:

Chemical structure of cyclostin

 Molecular formula of cyclostin is C7H15C12N2O2P·H2O
 Chemical IUPAC Name is 2-[bis(2-chloroethyl)amino] tetrahydro-2H-13,2-oxazaphosphorine 2-oxide monohydrate
 Molecular weight is 279.1 g/mol
 Cyclostin available : 25mg tablets, 50mg tablets

Generic name: Cyclophosphamide

Brand name(s): Clafen, Claphene, Cyclophosphamid, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphoramide, Cyklofosfamid, Cytophosphan, Cytoxan, Endoxan, Endoxan R, Endoxana, Endoxanal, Endoxane, Enduxan, Genoxal, Hexadrin, Lyophilized Cytoxan, Mitoxan, Neosar, Procytox, Semdoxan, Sendoxan, Senduxan, Zyklophosphamid

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