Cytoxan review

Cytoxan can be prescribed as Cytoxan Lyophilized and Neosar, or generically prescribed as cyclophosphamide. Given as an injection, this medication is designed to help fight cancer. It works by dramatically interfering with the rate of cancer cell multiplication which slows and sometimes even ceases their growth. This medication is used in conjunction with other cancer fighting remedies. A common secondary use for Cytoxan is the treatment of a rare but serious kidney disease known as nephritic syndrome in children.

There are risks involved with using Cytoxan for cancer treatment therapies. In a small percentage of patients, secondary cancers have been known to follow the long term use of this medication. The risk-benefit ratio should be carefully considered before prescribing Cytoxan.

Not all patients will be able to maintain a regimen therapy with this medication. A thorough medical history should be assessed prior to prescribing Cytoxan. Patients with a medical history including the need for a surgical procedure, heart disease, kidney disease, liver disease, the removal of adrenal glands, bone marrow issues, previous x-ray therapy, wounds that have not healed, have undergone treatment with other chemotherapy medications, recent vaccinations, recent infections, have low levels of white blood cells, or have a low platelet count may not be able to take Cytoxan or may require special cautious monitoring while undergoing drug therapy with this medication.

The American Food and Drug Administration has rated this medication as a category D pregnancy risk. This means that there is a high likelihood that Cytoxan would cause birth defects or damage to an unborn fetus. Men who have or are using this medication can also pass on birth defects when fathering a child. Women who are nursing are likely to cause harm to a nursing infant as this medication passes through the mother’s breast milk. Women who are nursing, pregnant, or may become pregnant should avoid taking this medication. If either partner in a sexual encounter is taking this medication, two forms of birth control are recommended.

A missed dose can be made up as soon as possible, regardless of whether the patient is taking the oral medication or is receiving injections of this medication. Patients who miss a dose should never take extra medication unless expressly directed by their prescribing physician. Doing so may cause an overdose.

An overdose requires immediate emergency medical attention. Symptoms of an overdose may include depressed bone marrow function, heart complications, or even an infection.

Side effects are common when taking Cytoxan. Mild side effects generally do not require medical attention. Patients should be encouraged to discuss these side effects with the prescribing physician. Mild side effects may include symptoms such as nausea, vomiting, loss of appetite, stomach pain, temporary hair loss, diarrhea, changes in finger or toe nails, alterations of skin color and texture, sores in the mouth, and sterility—either temporarily or permanently.

Serious side effects are generally rarer and require immediate medical care. Symptoms such as lower back pain, pain in the side, jaundice, painful urination, difficult urination, swelling, chest pain, respiratory distress, unusual bleeding and bruising, bone marrow problems, bloody urine, black stools, tarry stools, symptoms of an infection, or any signs of infection require immediate and urgent medical treatment.

There are medications that will negatively interact with or create ineffective medicines when combined with Cytoxan, Patients should never add any type of medication, herbal remedy, or vitamin supplements without express permission by the prescribing physician. Medications with a known history of interactions with Cytoxan include blood thinners, phenobarbitol, digoxin, allopurinol, thiazide diuretics, and additional chemotherapy medications.

Cytoxan has the following structural formula:

Chemical structure of cytoxan

• Molecular formula of cytoxan is C7H15C12N2O2P·H2O
• Chemical IUPAC Name is 2-[bis(2-chloroethyl)amino] tetrahydro-2H-13,2-oxazaphosphorine 2-oxide monohydrate
• Molecular weight is 279.1 g/mol
Cytoxan available : 25mg tablets, 50mg tablets

Generic name: Cyclophosphamide

Brand name(s): Clafen, Claphene, Cyclophosphamid, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphoramide, Cyclostin, Cyklofosfamid, Cytophosphan, Endoxan, Endoxan R, Endoxana, Endoxanal, Endoxane, Enduxan, Genoxal, Hexadrin, Lyophilized Cytoxan, Mitoxan, Neosar, Procytox, Semdoxan, Sendoxan, Senduxan, Zyklophosphamid

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