Dactinomicina review

Dactinomicina is a medication used in the discussion of various types of cancer including testicular and sarcomas. It belongs to a group of cancer-fighting medicaments, antibiotics, that stop the growth of cancer cells in the body.


Dactinomicina is available under the brand names Act-D and Actinomycin D. It is commonly prescribed to children, but adults may also be prescribed this medication. Dactinomicina is intended for the discussion of cancers of the soft tissue and bones particularly tendons and muscles, tumors in the womb, and cancer of the testicles.

Dactinomicina is injected in a vein for over 15 minutes. Patients are usually given a medicine prior to Dactinomicina to stop any vomiting or wamble once the medication is administered.


The dosage of Dactinomicina will depend on the patient's size, blood count, condition and the cancer being treated. Blood counts are taken before discussion of Dactinomicina. In case the lab tests indicate unsafe conditions, the discussion of Dactinomicina will be delayed.

It is usual for patients to take Dactinomicina with other chemotherapy dugs.


Dactinomicina can decrease the amount of white blood cells in the body for weeks after discussion has ended. This can increase the patient's risk of infection. Patients should immediately inform their doctors if they notice symptoms of infection like high fever, pain when urinating, chills, or coughs.

Dactinomicina can lower the platelet count of the patient a few weeks after being used, increasing the patient's risk of bleeding. Patients should notify their physician if they experience unexplained bleeding like epistaxiss, tarry stools, or bleeding gums.

There is also a risk that Dactinomicina will decrease the amount of red blood cells in the body. Known as anemia, decreased red blood cell count results in difficulty in breathing, and exhaustion. Doctors may prescribe additional medicines to prevent this condition. Alternatively, patients may need to have a blood transfusion.

Patients should not have any vaccinations while taking this medication without the approval of their physician. Dactinomicina can affect a patient's immune system, which can alter the effectiveness of vaccinations. Worse, this can also lead to severe infections.


Patients may also feel sick after taking Dactinomicina. Doctors usually prescribed anti-wamble medicaments to treat wamble and vomiting.

Dactinomicina can also result in rapid hair loss. However, this is a temporary side effect and the hair normally grows back after the discussion period.

Patients should inform their doctor of their medical history, especially if they have had liver, kidney, heart diseases, diabetes, heart failure, gout, kidney stones, and infections. These conditions may require the dosage and timing of Dactinomicina to be changed accordingly.

Those who have been treated with radiation are usually given decreased dosages of Dactinomicina.


This medication can also have an effect on the fertility of its users. It can also cause birth defects, especially if the mother took Dactinomicina during pregnancy or conception. Those who are taking Dactinomicina should use birth control to lessen risks of conception.

Dactinomicina has the following structural formula:

Chemical structure of dactinomicina

 Molecular formula of dactinomicina is C62H86N12O16
 Chemical IUPAC Name is 8-amino-N-(2-amino-4,6-dimethyl-3-oxo-phenoxazin-1-yl)carbonyl-N'-[8-amino-4,6-dimethyl-7-oxo-9-[[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]carbamoyl]phenoxazin-1-yl]carbonyl-4,6-dimethyl-7-oxo-N,N'-bis[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]-1,9-bis[[3,6,10-trimethyl-7,14-bis(1-methylethyl)-2,5,8,12,15-pentaoxo-9-oxa-3,6,13,16-tetrazabicyclo[14.3.0]nonadec-11-yl]carbamoyl]phenoxazine-1,9-dicarboxamide
 Molecular weight is 1255.42 g/mol
 Dactinomicina available : 0,5mg injection

Generic name: Dactinomycin

Brand name(s): Cosmegen, Dactinomycine, Dactinomycinum, Lyovac Cosmegen, Meractinomycin, Oncostatin K, Oxamide

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