is a brand name for a generic non-steroidal medication containing calcipotriol
, which is similar to Vitamin D
. It is prescribed for the treatment of skin affected by psoriasis
. Psoriasis occurs as the result of over active skin cells; Daivonex is used to treat those skin cells. It is applied to plaques—raised, rough, reddened areas covered with thin, silvery scales-- on the skin. Daivonex is available as an ointment, a cream, and a scalp solution. It should be applied twice a day, in the morning and at night.
Daivonex is not to be used for certain types of psoriasis. If you have widespread psoriasis all over your body, this is not an appropriate treatment. Also, if you suffer from types of psoriasis such as guttate, generalized pustular psoriasis, or erythrodermic psoriasis, Daivonex is not indicated for your condition. You should also avoid getting it on your unaffected skin, as it may cause irritation.
Daivonex is safe for most people, but there are some people who should consult a doctor before using it. If you are allergic to calcipotriol or any medication that contains it, you may have a negative reaction to Daivonex. An allergic reaction would include difficulty breathing, wheezing, swelling
of the throat, face, lips
, or tongue
, a rash or hives
. You should also not use Daivonex if you have high levels of calcium
in your blood
, or if you are taking calcium, Vitamin D supplements, or other medications that have compounds similar to Vitamin D in them. You should also make sure your doctor knows if you have any kidney
problems or any other illness. Daivonex ointment can be used in conjunction with other treatments for psoriasis, but the cream and scalp solution should not be used with other medications. You should not use Daivonex on your face, as it may cause a rash to develop. You should also not put bandages or other tight coverings on the affected area; Daivonex allows you to wear your own clothes.
Side effects are very rare in Daivonex, but may include the following conditions or symptoms: burning sensation, stinging sensation, skin irritation, dry skin, eczema
, worsening of your psoriasis, darkening of the skin, bleaching of the skin, or increased sensitivity to light. You could also experience various types of rashes, such as scaly or pustular. Other side effects include having too much calcium in your blood, crystals in your urine, and upset stomach
with or without diarrhea
Make sure to tell your doctor if you are pregnant or are planning to become pregnant. It has not been established whether Daivonex is safe during pregnancy, though animal tests have not shown it to cause birth defects. If you are using Daivonex on psoriasis plaques
on your breasts
, you should not breast
feed a baby. Daivonex ointment may be used for up to eight weeks on children, but neither Daivonex cream nor scalp solution is recommended for pediatric use.
Daivonex has the following structural formula:
• Molecular formula of daivonex is C27H40O3
• Chemical IUPAC Name is 1R,3S)-5-[2-[(1R,3aR,7aS)-1- [(2S)-5-cyclopropyl-5-hydroxy-pent-3-en-2-yl]-7a- methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene] ethylidene]-4-methylidene-cyclohexane-1,3-diol
• Molecular weight is 412.605 g/mol
• Daivonex available : 0.005% cream 120gm tube, 0.005% cream 60gm tube, 0.005% ointment 120gm tube, 0.005% solution 60ml bottle