is used for the treatment of various skin disorders such as eczema
. It is available in ointment and an emollient cream.
Dermovate, which has a generic name of clobetasol
propionate, is recommended for use among adults and children. Dermovate is an anti-inflammatory and antipruritic. It is recommended for patients suffering from various skin disorders like eczema, rashes, allergies
, and dermatitis
. The medication reduces the skin edema, redness, and itching
that comes with these skin disorders.
Dermovate is applied to the skin twice a day. However, a physician can increase the dose according to the severity of the condition. The medication should be used only to the skin and should never be applied to the face, underarms, or groin unless instructed by your physician.
Patients should first wash and dry their hands before applying Dermovate. The affected area should be cleaned and dried prior to the application of the medication as well. The area should not be covered or bandage unless instructed to do so by your physician.
After applying Dermovate, patients should again wash their hands. In case the medication accidentally comes in contact with the eyes, mouth
, or nose
, immediately rinse the area with lots of water.
Dermovate should not be used for longer than 2 weeks and the dose should be kept under 50 grams a week. In case the conditions continue, patients should consult their physician for further direction.
Patients should inform their doctor if they experience any side effects. Some of the side effects that may result include a burning, itching, or stinging sensation at the area being treated. Usually these should improve after a few days once the body becomes used to the medication. However, if the conditions persist, patients should talk to their doctor as soon as possible. Most of the time, patients using Dermovate do not experience these side effects, so the chances are quite low.
Some serious side effects include discoloration of the skin, acne
, stretch marks, unwanted growing of hair, and folliculitis or hair growth.
It is also very rare that a patient develops atopy to this medication. However patients are advised to get immediate medical help in case they notice symptoms of an allergic reaction including rashes, skin edema, itching, severe dizziness
, and difficulties in breathing.
Before taking Dermovate, patients should tell their doctors if they have any history of allergies to corticosteroids like prednisone
or if they are allergic to any medication. Patients should also tell their doctor their medical history, particularly if they have problems in blood
circulation or immune system, and skin disorders like rosacea
Clobestasol should not be used on a sore or infected area.
There is also a possibility-albeit very low-that Clobestasol can enter the bloodstream. It can lead to undesirable results requiring corticosteroid treatment. This may happen to children or those who use the medication for an extended period of time. Some of the symptoms that may arise as a result include vision problems, unexplained weight loss
, and persistent headache
Dermovate has the following structural formula:
• Molecular formula of dermovate is C25H32ClFO5
• Chemical IUPAC Name is [17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
• Molecular weight is 466.97 g/mol
• Dermovate available : 0.05% cream 15gm tube, 0.05% cream 30gm tube, 0.05% cream 45gm tube, 0.05% cream 60gm tube, 0.05% gel 15gm tube, 0.05% gel 30gm tube, 0.05% gel 60gm tube, 0.05% ointment 15gm tube, 0.05% ointment 30gm tube, 0.05% ointment 45gm tube, 0.05% ointment 60gm tube, 0.05% solution 50ml bottle