Desonide review

Desonide, a medicament used to treat bronchial asthma and those suffering from a range of respiratory problems related to nasal problems, is a glucocorticoid steroid that interacts with hydrocortisone or cortisol, the two chemicals naturally produced by the body via the adrenal glands. Its main effect upon inhalation is that of an anti-inflammatory, which lessens the possible reaction of the airways prior to asthma attacks. This causes a retardation of the initial hypersensitivity of the main airways, preventing spasms and allowing air to pass through more easily for proper respiration.

Desonide should not be given during an asthma attack but only as a preventive measure for future asthma attacks.

Desonide is given to patients who have problems with hypersensitivity attacks that entail constricting of airways. It may be given to patients who have allergic reactions that also lead to the same constriction pattern. Desonide is used to treat long-term ailments for asthma and is recommended for patients who have difficulty breathing at night or those with paroxysmal nocturnal asthma attacks.

This medicament should not be given to patients suffering from acute attacks of asthma. Usually, this medicament is given to patients who are more than six years of age. The immediate effects of the medicament may be seen as early as 24 hours after initial administration, while full effects will be significantly seen within 1 to 2 weeks.

For adults, the typical prescription is 1 to 4 puffs, two times a day. For children, the prescription is typically halved, with 1 to 2 puffs, twice per day. There are some instances where doctors will use this medicament to treat mild asthma. The number of puffs would still be based on the age of the patient, but the frequency per day would be halved.

Some side effects of this medicament include a mild cough or wheezing. A bronchodilator such as Ventolin, or any albuterol medicament usually counters this side effect. This counter medicament is taken prior to taking Desonide to prevent the occurrence of the side effect.

There are some instances where oral thrush may thrive. Usual statistics are about 1 in every 25 patients, but this is considered to be due to either a weakened immune system or improper hygiene especially in between puffs.

A long-term side effect of the glucocorticoid content of Desonide may alter or decrease the calcium and bone formation of patients, which may cause osteoporosis.

Desonide's interaction with other medicaments is very minimal, except for those using Ketoconazole. It is documented that the presence of Ketoconazole in the body increases the amount of retained Desonide. This may account for the increased chance of a side effect. General precautions should be given to those who are pregnant.

Desonide has the following structural formula:

Chemical structure of desonide

• Molecular formula of desonide is C25H34O6
Desonide available : nasal spray 32 mcg

Generic name: Budesonide

Brand name(s): Bidien, Budeson, Cortivent, Desowen, Entocort, Micronyl, Preferid, Pulmicort, Rhinocort, Rhinocort Aqua, Spirocort, Tridesilon

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