Diane belongs to a group of medications called antiandrogen that suppresses the activity of testosterone on the tissues. It blocks the androgen receptors, preventing the androgen from joining with them while suppressing the growth of luteinizing hormones.
DIANE ACTIONDiane is available under the brand names Procur, Androcur, Cyprone, Cyprostat, Cyprohexal, Cyrproteron, Cyproteronium, Ciproterona, Neoproxil, and Silterone. It is recommended for individuals who have prostate cancer, hypersexuality, priapism, and benign prostatic hyperplasia. It can also be used for the treatment of hirsutism.
Diane is sometimes used to cure hot flashes because it can act like progesterone. In other countries it is also used to cure acne and male-pattern hair growth.
DIANE DOSAGEThe dosage of Diane depends on the condition of the patient. The usual dose of Diane as an oral contraceptive is 2 mg per day taken once for 21 days. This is followed by a week-long interval using placebo pills.
For hypersexuality, hirsutism, and transexuals, a dosage of 25 mg taken twice a day should be enough, although the dosage can be increased. Since chances of side effects increase with higher dosages, it is advisable that patients take the lowest dosage possible.
Dosage of Diane for the cure of prostate cancer can go up to 300 mg per day, although high doses can increase the risk of severe hepatic toxicity requiring close monitoring. Diane is usually co-administered with medications like 5-alpha reductase inhibitors for the treatment of prostate cancer.
DIANE SIDE EFFECTSThe most severe side effect caused by the use of Diane is liver toxicity. Patients are usually monitored for changes in the liver enzymes, especially those who take doses of 200-300 mg per day. Toxicity depends on the dosage, so those who use Diane as a birth control tool usually have low risk of suffering from liver toxicity.
Diane can result in suppressed adrenal function. It has also been associated with changes in mood, particularly depression among patients, probably caused by deprivation of androgen.
Patients may also suffer from side effects including nausea, cramps, vomiting, headache, spotting, decreased sexual desire, and breast tenderness. In case any of these side effects worsen or persist, patients should immediately inform their doctors.
Some of the more serious side effects of Diane include swollen or painful leg, blurred vision, and dizziness. Other severe side effects may include irregular heartbeat, weakness, dark urine, yellowed skin or eyes, pain in the abdomen, and irregular urination.
DIANE PRECAUTIONSDiane should be used with caution in patients who have a history of depression as well as those who have diabetes. Diane may cause changes in one’s glucose metabolism. This medication can also aggravate the risks of thromboembolism and other alter lipid profiles.
DIANE DURING PREGNANCYDiane is not recommended for pregnant women. For women who are of childbearing age, the medication should be given with a complementary oral contraceptive. Additional Diane may be taken to ensure that the medication does not disturb the regular withdrawal bleeding.
Diane has the following structural formula:
Molecular formula of diane is C22H27ClO3
Molecular weight is 374.9010 g/mol
Molecular weight is 374.9010 g/mol
Generic name: Ethinyl estradiol
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