Diclofenac review

Diclofenac—which is marketing under the brands Voltaren, Diclon Voltarol, the Flector patch, Zolterol, Vetagesic, Deflamat, Dedolor, Arthrotec, Voveran, Olfen, Abitren, Modifenac, Rhumalgan, Panamore, Pennsaid, Cataflam, Difene, Difen, and Dicloflex, plus various drug dose combinations—is a nonsteroidal anti-inflammatory drug or NSAID administered to patients suffering from inflammation and as an analgesic to reduce pain in conditions such as acute injury or arthritis. It can also decrease dymenorrhea or menstrual pain. Its generic name is taken from its chemical name, which is 2-(2,6-dichloranilino) phenylacetic acid.

In the United States, India, and the United Kingdom, it may be supplied as either sodium or potassium salt—in China, it is most often distributed as sodium salt, while in other countries it's only available only as potassium salt. Diclofenac is also available as a generic drug in numerous formulations. Over the counter (OTC) use is approved in some countries for fever associated with common infections as well as minor aches and pains.

The maximum recommended dose for diclofenac sodum in any dosage form is 150 milligrams daily. In particular, Apo-Diclofenac tablets should be swallowed whole without crushing or chewing them and taken with food. 100 to 150 milligrams is the typical initial daily dose range; in mild cases, Apo-Diclofenac treatment should be started with 75 to 100 milligrams every day.

Overall, a patient's daily dose of diclofenac should be divided into two or three fractional doses. It's because the action of one single dose is much longer—from six to eight hours—than the very short half-life that the medication indicates. Part of the reason for this is due to a specific high concentration achieved in synovial fluids.

Be duly warned that NSAIDs like diclofenac can increase your chances of life-threatening blood circulation or heart ailments, including stroke or heart attack. This risk will escalate the longer you use diclofenac-based products or any other NSAIDs. With that said, you should also not use diclofenac just before or after having coronary artery bypass graft/CABG/heart bypass surgery.

NSAIDs can also cause serious side effects on your intestine or stomach, including bleeding or perforation. These types of ailments can be deadly and gastrointestinal maladies can happen without any warning at any time while you're undergoing NSAID treatment. Older adults and the elderly also have a greater chance of getting these severe sicknesses as well.

You shouldn't use any OTC medication for pain, cold, or allergy without first consulting your pharmacist or physician. Many drugs available over the counter contain aspirin or other medicines like diclofenac such as naproxen, ketoprofen, and ibuprofen. Simply put, if you take certain products together with diclofenac, you may accidentally take too much of this type of medication and suffer from the consequences of overdose. As such, you must read the label of any other medicine you're using to see if it contains naproxen, ketoprofen, ibuprofen, or aspirin.

You must not drink any alcoholic beverage when taking this drug, because alcohol can increase your chances of stomach bleeding care of this medication. You must also prevent yourself from being exposed to sunlight or artificial ultraviolet rays from tanning beds or sunlamps while undergoing diclofenac treatment because this medicine can make your skin more photosensitive, thus resulting in a propensity to sunburn.

If you have symptoms of heart or circulation problems such as chest pain, problems with vision or balance, slurred speech, shortness of breath, and bodily weakness, seek prompt emergency medical help. Diclofenac can also increase your risk of getting a sickness of the stomach or intestine, including internal bleeding or perforation of the stomach or intestinal walls. These gastrointestinal maladies may prove fatal and can occur without warning while you continue taking diclofenac.

As mentioned earlier, the elderly must be wary of taking this medication as well, because they are more susceptible to its side effect, particularly gastrointestinal conditions. In any case, contact your healthcare specialist if you have symptoms of stomach or intestinal bleeding, which includes coughing up blood or vomit that look like coffee grounds and expelling black, bloody, or tarry stools.

Diclofenac has the following structural formula:

Chemical structure of diclofenac

• Molecular formula of diclofenac is C14H11Cl2NO2
• Chemical IUPAC Name is 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid
• Molecular weight is 296.148 g/mol
Diclofenac available : 50mg tablets

Brand name(s): Allvoran, Assaren, Benfofen, Cataflam, Combaren, Delphimix, Dichlofenac, Dichronic, Diclobenin, Diclord, Dicloreum, Dolobasan, Duravolten, Ecofenac, Effekton, Emulgel, Klipal, Kriplex, Neriodin, Novapirina, Novo-Difenac, Pennsaid, Primofenac, Prophenatin, Rhumalgan, Solaraze, Tsudohmin, Valetan, Voldal, Voltaren, Voltaren Plus, Voltarol, Xenid

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