Dicyclomine review

Dicyclomine is a drug that treats stomach or intestinal disorders. Irritable Bowl Syndrome is one of these disorders, as well as colic spasms, diverticulosis and bladder spasms. What it does is reduce the contractions of the muscles in the gastrointestinal tract, specifically the gut and the stomach. It also reduces the stomach acid that is being produced, also to relieve stress from the gastrointestinal tract.

Usually drugs interact with each other in different ways. Sometimes when two different drugs are taken together they counteract each other and produce negative effects on a patient’s health. Before using Dicyclomine be sure to tell your doctor if you are taking any of the following drugs: antacids, antidepressants, antihistamines, diet pills, asthma medicine, pain relievers (such as Demerol), monoamine oxidase (MAO) inhibitors, amitriptyline also known as Elavil, and doxepin more commonly known as Adapin or Sinequan. To be safe, just disclose all the medication that you are taking to your treating physician. Some drugs actually counter the effects of Dicyclomine. Cisapride like the drug Propulsid or Reglan can reverse the effects of Dicyclomine, when taken together the body is actually stimulated to be more active and the stomach is tenser and tighter.

Another precaution that all patients should take before accepting a new drug is to disclose all previous illnesses to the doctor. In this case the drug Dicyclomine affects the stomach so patients should tell the doctor about any recent operations or problems with the stomach. Also inform your doctor if you have had glaucoma, have difficulty urinating, an enlarged prostate, hyperthyroidism, liver or kidney disease, and heart disease. All this information will help your doctor make the best prescription he can for your unique case.

Please remember that this drug causes drowsiness in most people, so patients being treated by it should not operate heavy machinery or drive. It might be dangerous for them and for others. Taking this drug as well as other drugs that cause sleepiness, like anti histamines or the anti-anxiety drugs (Valium, Ativan, Xanax), can increase the level of sleepiness. Patients taking both kinds of drugs should watch out for that double effect. Also note that Dicylomine prevents the body from cooling off by sweating, so in various hot temperatures people might be more prone to heat stroke and fever if they are taking this drug.

Some side effects to taking this drug are: stomach ache, vomiting, constipation, dizziness, weakness, vision problems, loss of appetite, bloating, urination problems and gas problems. These side effects are harmless and easily manageable. However, there are some side effects that are like early warning signs for an allergic reaction to the drug. These are: confusion, hallucination (very rare cases), unexplained and radical mood swings, fainting, rashes, swelling, and itching. If any of these symptoms arise in an extreme case please don’t hesitate to go to the doctor immediately.

Dicylomine is usually marketed under the name Bentyl. And it comes as a tablet and syrup. The tablets range from 10mg – 20mg. Patients usually start out ingesting 20mg four times a day but the doctor might increase the dose as time goes by. This drug actually works best when it is taken at the same time everyday.

Dicyclomine has the following structural formula:

Chemical structure of dicyclomine

• Molecular formula of dicyclomine is C19H35NO2
• Chemical IUPAC Name is 2-diethylaminoethyl1-cyclohexylcyclohexane-1-carboxylate
• Molecular weight is 309.487 g/mol
Dicyclomine available : 10mg capsules, 20mg tablets

Brand name(s): Atumin, Bentomine, Bentyl, Bentylol, Dicicloverina, Dicycloverin, Dicycloverine, Dicycloverinum, Diocyl, Dyspas, Formulex, Kolantyl Hydrochloride, Mamiesan, Merbentyl, Oxityl-P, Procyclomin, Sawamin, Spasmoban, Wyovin

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