Diltahexal is a brand name for the generic medication diltiazem hydrochloride, which belongs to a group of medications called calcium blockers. It works by relaxing the muscles of your heart and blood vessels to allow for the passage of more blood volume. It is given in extended release tablets, taken once a day, for the treatment of high blood pressure, or hypertension, and for the treatment of chronic angina, or chest pains, and certain heart rhythm disorders. It may be used alone or in conjunction with other medications.
Very serious side effects are rare with Diltahexal treatment. Some of the most common side effects include swelling in the legs and feet, dizziness and fatigue, all of which occur in a very small percentage of patients. Other side effects can include blockage of the atria, cough, irregular or fast heartbeat, headache, congestive heart failure, low blood pressure, sleep disturbances, thirst, eye irritation, memory loss, depression, tingling or numbness, ringing in the ears, or tremor. You may also experience loss of appetite, abnormal gait, constipation or diarrhea, nosebleeds, impotence, muscle cramps, runny nose, weight gain, dry mouth, too much protein in the blood, sensitivity to light, frequent urination at night, development of breast tissue in men, skin discoloration, itchy skin, low white blood cell count, and peeling skin. You should call your doctor immediately if you have any of the following: fast or slow heartbeats, dark urine or clay-colored stools, jaundice, fever, sore throat or headache with a severe blistering, peeling, and red skin rash.
Some drugs do not interact well with Diltahexal. If you are taking St. John’s Wort, rifampin, lovastatin, dexamethasone, Tagamet, cyclosporine, antibiotics, antidepressants, HIV/AIDS medications, seizure medications, or a beta-blocker, you may not be allowed to begin a course of treatment with Diltahexal. Your doctor and you may have to decide whether to adjust your dosages of Diltahexal or to pursue and another course of treatment.
You should not take Diltahexal if you suffer from certain heart conditions, including “sick sinus syndrome,” or “AV block,” unless you have a pacemaker, or if you have recently had a heart attack. You should also make sure to let your doctor know if you are allergic to any drugs, are taking any other drugs, including over the counter or herbal medications, or if you have kidney disease, liver disease, or congestive heart failure.
Diltahexal is in Pregnancy Category C, which means that it is not known whether it is harmful to a pregnancy or to the development of a fetus. There have been no conclusive studies done in pregnant women, so you should use caution when taking Diltahexal if you are pregnant or planning to become pregnant. It is known, however, that Diltahexal passes into breast milk, so if you are breastfeeding a child, you should discontinue using Diltahexal. If you plan to continue using Diltahexal, you should explore other options for feeding your baby. Diltahexal has not been evaluated for use in children, so it is not recommended for pediatric use.
Diltahexal has the following structural formula:
• Molecular formula of diltahexal is C22H26N2O4S
• Chemical IUPAC Name is [2-(2-dimethylaminoethyl)-5-(4-methoxyphenyl)-3-oxo-6-thia-2-azabicyclo [5.4.0]undeca-7,9,11-trien-4-yl]ethanoate
• Molecular weight is 414.519 g/mol
• Diltahexal available : 30mg tablets, 60mg tablets, 90mg tablets, 120mg tablets
Generic name: Diltiazem
Brand name(s): Acalix, Adizem, Altiazem, Anginyl, Angizem, Anoheal, Apo-Diltiaz, Britiazim, Bruzem, Calcicard, Cardizem, Citizem, Cormax, Deltazen, Dilacor, Diladel, Dilcontin, Dilpral, Dilrene, Dilt-cd, Diltia, Diltiazem HCL, Dilticard, Dilzem, Dilzen, Endrydil, Herbesser, Masdil, Novo-Diltazem, Nu-Diltiaz, Syn-Diltiazem, Tiazac Tildiem
Review published on: 05 April 2008
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