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  Diltiazem

 


Diltiazem

Diltiazem review by Medicalook.com




Diltiazem is a popular heart medication that is part of a larger group of drugs called benzothiazepines. As a group benzothiazepines, are calcium channel blockers, which means that they manipulate the level of calcium in he heart to ensure a smoother and stronger heart beat. Diltiazem in particular is a vasilator, meaning that it increases the blood flow and decreases the heart rate. It facilitates a stronger and slower heart beat. This is the perfect drug for diseases like angina pectoris, which is when you don’t get enough blood and oxygen to your heart. It is also used to treat hypertension, or high blood pressure; and arrhythmia, when there is abnormal electric activity in the heart.

Most drugs have harmless side effects that are really just a sign that the drug is working it’s magic on your body. Common side effects are nothing to worry about, Diltiazem has side effects like: hypotension, bradycardia, dizziness, flushing, constipation, tiredness, slight narcolepsy, slow heartbeat and dry mouth. However, some reactions to the drug might be symptoms for an allergic reaction, these symptoms are: swelling of the face or limbs, rashes, yellowing of the eyes and skin, difficulty breathing or swallowing and severe chest pain then you should go t6o a doctor immediately.

Sometimes we take two or more medications and their combination might not be healthy for our body. Even the vitamins can sometimes have a bad reaction with certain drugs. Diltiazem has a sensitive reaction to these drugs: beta-blockers, digoxin, quinidine, diuretics, cyclosporine, fentanyl, medications to treat depression (Valium), medications to treat glaucoma, and natural vitamins and supplements. It’s important to give a complete and comprehensive medical history to your doctor. This will help him in choosing the proper dosage for you. It’s important that he know if you have had any heart, liver or kidney diseases or operations on those organs. It is important to know if these parts of your body are sensitive because the drug affects them in its course of treatment. They might have a bad reaction to the drug if they are sensitized or weak.

It is generally recommended that pregnant women do not take this drug. While no conclusive research has been presented that it affects the fetus, several studies show that medications of this kind sometimes lead to abnormalities. It’s better to be safe than sorry, especially when it comes to children. Another warning is for nursing mothers. Drugs often pass through the milk to a nursing child, so it is advisable that you stop breastfeeding for as long as you are on Diltiazem.

It is generally recommended that you keep tabs on how well your heart rate is while you’re on this drug. Ask your doctor to teach you how to take your own heartbeat and try to monitor how well you’re doing. Diltiazem is marketed under many different names because of it’s popular use all over the world. Cardizem, Cartia XT, Tiazac, Tiazac XC, Tiamate, Tildiem, Adizem, Viazem, and Dilatam are all names under which Diltiazem is sold.
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Diltiazem has the following structural formula:

Chemical structure of diltiazem


• Molecular formula of diltiazem is C22H26N2O4S
• Chemical IUPAC Name is [2-(2-dimethylaminoethyl)-5-(4-methoxyphenyl)-3-oxo-6-thia-2- azabicyclo[5.4.0]undeca-7,9,11-trien-4-yl]ethanoate
• Molecular weight is 414.519 g/mol
Diltiazem available : 30mg tablets, 60mg tablets, 90mg tablets, 120mg tablets



Brand name(s): Acalix, Adizem, Altiazem, Anginyl, Angizem, Anoheal, Apo-Diltiaz, Britiazim, Bruzem, Calcicard, Cardizem, Citizem, Cormax, Deltazen, Dilacor, Diladel, Dilcontin, Dilpral, Dilrene, Dilt-cd, Diltahexal, Diltia, Diltiazem HCL, Dilticard, Dilzem, Dilzen, Endrydil, Herbesser, Masdil, Novo-Diltazem, Nu-Diltiaz, Syn-Diltiazem, Tiazac Tildiem


Review published on: 21 April 2008

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