Dovonex, which is generically prescribed as calcipotriene topical, is commonly used to treat plaque psoriasis. Plaque psoriasis is a skin condition that leaves scaly patches on the skin’s surface. Dovonex is a synthetic form of vitamin D and helps in the promotion of new growth and development of healthy skin cells.
Dovonex is not appropriate for everyone. A thorough medical history should be assessed prior to prescribing this medication. Patients with a medical history which includes current sunburn, rashes other than psoriasis, windburn, chapped, dry, or irritated skin may not be able to use Dovonex or may require careful monitoring while undergoing drug therapy with this medication, depending on the condition and the severity of the condition.
The American Food and Drug Administration rated this medication as a pregnancy risk category C. It has yet to be determined whether or not Dovonex causes harm or birth defects in unborn babies. It also has yet to be determined whether or not this medication passes through the mother’s breast milk and affects a nursing baby. The prescribing physician should avoid prescribing this medication to women who are pregnant, nursing, or have a high likelihood of becoming pregnant.
There is a risk of side effects associated with Dovonex, some of which are severe. A patient who is experiencing a serious side effect or an allergic reaction should seek immediate emergency medical attention. An allergic reaction will present with symptoms such as facial swelling, including swelling of the lips, mouth, tongue, or throat, hives, and difficulty breathing. Other serious side effects which require emergency medical care include symptoms such as severe changes in skin color or severe burning.
Less serious side effects typically do not require emergency medical attention but should be reported to the prescribing physician. Patients should be encouraged to report all side effects. Less serious side effects include symptoms such as redness, swelling, itching, burning, tingling, dryness, peeling, or less than severe changes in skin color. Less serious side effects can often be reduced to a tolerable level by reducing the dosage of Dovonex.
Dovonex should be applied exactly as it has been prescribed by the physician. If the patient misses a dose, the dose should be applied as soon as it is remembered. However, if it is almost time for the next scheduled application, the missed dose should be skipped to avoid the potential for an overdose. The patient should never take a double dose of this medication. If an overdose is suspected, the patient should seek immediate emergency medical attention. An overdose may present with symptoms that include elevated blood calcium levels, dizziness, weakness, fatigue, drowsiness, headache, decreased appetite, nausea, and vomiting.
There is a risk of negative drug interactions associated with Dovonex. A thorough medical history should be understood prior to prescribing this medication. Patients should be urged to inquire with the prescribing physician before taking any new medications, including over the counter medications and herbal remedies. Medications with a known drug interaction with Dovonex include any other topical treatments for skin, including itch, acne, or topical antihistamine medication. Any harsh or abrasive cleaners, cosmetics, acne treatments, and perfumes may cause excessive irritation to the skin undergoing treatment. Washing the area too much may irritate the skin to the point that medication can not be used.
Dovonex has the following structural formula:
• Molecular formula of dovonex is C27H40O3
• Molecular weight is 412.6 g/mol
• Dovonex available : 0.005% cream 120gm tube, 0.005% cream 60gm tube, 0.005% ointment 120gm tube, 0.005% ointment 60gm tube, 0.005% solution 60ml bottle
Generic name: Calcipotriene
Review published on: 07 April 2007
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