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Famotidine

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Famotidine

Famotidine review





Famotidine belongs to a group of H2 blockers that inhibits the production of acid in the stomach, and is commonly used to treat gastroesophageal reflux disease and peptic ulcer disease. This drug is also given to surgery patients prior to their operations to reduce the risk of aspiration pneumonitis and post-operative nausea. Zollinger-Ellison syndrome (a medical condition that increases production of stomach acid due to tumors in the pancreas and small intestine) can also be medicated with Famotidine. This drug is commonly marketed by the drug company Merck under the trade names Pepcid and Pepcidine.

There are available over the counter preparations of Famotidine in various countries. Over the counter preparations are used to treat and prevent sour stomach (caused by drinking or eating certain beverages and food) and heartburn. In the United States, Famotidine is available in preparations of 20 mg and 10 mg tablets combined with a traditional antacid. Large doses if this drug require a doctor’s prescription before it can be purchased.

Famotidine can either come in a suspension or tablet form and should be taken orally. It is usually taken once daily before going to sleep. There are several forms of over-the-counter famotidine such as chewable tablet form, tablet form and capsule. To effective prevent symptoms of heartburn and stomach hyper-acidity, Famotidine should be taken 15 to 60 minutes prior to taking a meal that may cause heartburn. eating foods or drinking drinks that may cause heartburn. For Famotidine in suspension form, the bottle must be shaken well before each use so that the mixture can be eenly mixed and there will be no settling down at the bottom of the bottle. Chewable Famotidine tablets must be chewed and grinded well before swallowing and should be followed by a full glass of water.

It is not advisable to take more than two capsules or tablets of Famotidine within 24 hours because it may produce counter-productive results. In addition, intake of over-the-counter Famotidine should not last for more than 2 weeks unless the doctor prescribed that one should do so. If symptoms of acid indigestion, heartburn and/or sour stomach persist even after 2 weeks of Famotidine intake, a visit to the doctor is highly needed.

If you are allergic to nizatidine, cimetidine or ranitidine, you should inform your doctor or pharmacist before you take Famotidine. You should not take over-the-counter Famotidine together with other medications for heartburn unless your doctor advised you to do so. People with phenylketonuria should also be careful in taking Famitidine because these medical condition can facilitate mental retardation if a specific diet is not followed. Women who are planning to become pregnant, are pregnant or breastfeeding should also inform their doctor prior to taking Famotidine.

Minor side effects include headache, diarrhea, dizziness, and constipation. More serious side effects include difficulty breathing or swallowing, hives, hoarseness, itching and skin rash. If any of these symptoms are too intense or persistent, a visit to the doctor is highly suggested.

Famotidine has the following structural formula:

Chemical structure of famotidine


• Molecular formula of famotidine is C8H15N7O2S3
• Chemical IUPAC Name is 2-[4-[2-(amino-sulfamoylimino-methyl)ethylsulfanylmethyl]- 1,3-thiazol-2-yl]guanidine
• Molecular weight is 337.449 g/mol
Famotidine available : 40mg/5ml suspension 50ml bottle, 20mg tablets, 40mg tablets

Brand name(s): Amfamox, Antodine, Apogastine, Bestidine, Blocacid, Brolin, Cepal, Confobos, Cronol, Cuantin, Digervin, Dinul, Dipsin, Dispromil, Dispronil, Duovel, Durater, Evatin, Fadin, Fadine, Fadyn, Fagastine, Famo, Famocid, Famodar, Famodil, Famodin, Famodine, Famogard, Famonit, Famopsin, Famos, Famosan, Famotal, Famotep, Famotidina, Famotidinum, Famotin, Famovane, Famowal, Famox, Famoxal, Famtac, Famulcer, Fanobel, Fanosin, Fanox, Farmotex, Ferotine, Fibonel, Fluxid, Fudone, Ganor, Gaster, Gastridan, Gastridin, Gastrion, Gastro, Gastrodomina, Gastrofam, Gastropen, Gastrosidin, Hacip, Huberdina, Ingastri, Invigan, Lecedil, Logos, Mensoma, Midefam, Mosul, Motiax, Muclox, Neocidine, Nevofam, Notidin, Nulceran, Nulcerin, Panalba, Pepcid, Pepcidin, Pepcidina, Pepcidine, Pepdif, Pepdine, Pepdul, Pepfamin, Peptan, Peptidin, Peptifam, Pepzan, Purifam, Quamatel, Quamtel, Renapepsa, Restadin, Rogasti, Rubacina, Sedanium-R, Sigafam, Supertidine, Tairal, Tamin, Tipodex, Topcid, Ulcatif, Ulceprax, Ulcofam, Ulfagel, Ulfam, Ulfamid, Ulfinol, Ulgarine, Vagostal, Weimok, Whitidin, Yamarin

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