Felodipine review

Felodipine is a calcium antagonist or a calcium channel blocker prescribed to treat high blood pressure (hypertension). It works by relaxing the blood vessels in the body so that the heart does not have to pump very hard. AstraZeneca markets it with the brand name Plendil.

Felodipine comes in tablet form to be taken orally and is usually taken once a day only. It is not advisable to divide, chew or crush Felodipine tablets because it may interfere with the effect of the drug. It should be noted that Felodipine does not cure high blood pressure; it only decreases and controls the symptoms of high blood pressure. Even if an individual already feels fine after taking one or two tablets of Felodipine, the medication should not be halted without referring it to a doctor first.

Before taking Felodipine, you should inform your doctor if you are allergic or have some history of being allergic to Felodipine. If you are taking medicines that have ingredients like carbamazepine, Phenobarbital, phenytoin, cimetidine, erythromycin, itroconazole, ketoconazole, and ranitide, you should tell your doctor about it so as to lessen the chances of the medicines clashing with each other. If you have a heart, liver or kidney disease, it would be best if you inform your doctor about it to make sure that your other medications won’t interfere with your Famotidine medication. Women who are planning to be pregnant, are pregnant or breastfeeding should also consult with their doctor prior to Famotidine intake to ensure the health of the baby.

If you have liver disease or any other kind of heart disease such as sick sinus syndrome, heart failure, low blood pressure, aortic stenosis or coronary heart disease, you may not be able to take Felodipine or you may have to take an adjusted dosage along with a closely-monitored treatment.

Recent findings have suggested that taking Felodipine with grapejuice is not advisable because it can cause toxic or abnormal effects. Tell your doctor if you have grapejuice in your diet or if you took Felopidine with grapejuice so that immediate medical intervention can be given.

Alcohol intake must be lessened or stopped when taking Felodipine because alcoholic beverages may cause further lowering of the blood pressure as well as worsen the drowsy and dizzy feeling of a person.

Some minor side effects of Felodipine include enlargement of gum tissue around the teeth, headache, constipation, hot flushes, heartburn, light-headedness, dizziness, palpitations and over-all body weakness. Serious side effects include rashes, difficulty breathing or swallowing, fainting spells, and swelling of the face, lips, tongue, eyes, legs or arms.

There may be times when one may get dizzy when he or she attempts to sit or stand up from a lying position. Changing positions while sleeping may even induce dizziness when one is under Felodipine medication.

Any aversive symptoms must be reported immediately to the doctor so that the medication can be stopped or regulated to suit the tolerance of the individual.

Felodipine has the following structural formula:

Chemical structure of felodipine

• Molecular formula of felodipine is C18H19Cl2NO4
• Chemical IUPAC Name is methylethyl4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• Molecular weight is 384.253 g/mol
Felodipine available : 2.5mg tablets, 5mg tablets, 10mg tablets

Brand name(s): Agon, Faropenem, Feloday, Felodipina, Felodipinum, Felodur Er, Felogard, Flodil, Hydac, Lexxel, Modip, Munobal, Penedil, Perfudal, Plandil, Plendil, Preslow, Prevex, Renedil, Splendil

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