Florone review

Florone is a corticosteroid that is marketed as a topical ointment containing the medicament. Florone is primarily used for its anti inflammatory and anti-itch qualities, much like most corticosterosis.

Corticosteroids are medicaments whose basic action is to reduce the activity of chemicals that make the trunk swell, itch and inflame. Topical corticosteroids like Florone work when they are absorbed by the skin, reacting to the chemicals that make that part of the skin inflamed.

Florone has been widely considered a topical medicament with a higher potency than other corticosteroids.

Topical Florone is used to treat skin conditions such as inflammation and pruritus, which may be caused by allergic reactions, psoriasis or eczema. Florone is also used to treat lichen sclerosus and a form of T-cell lymphoma called mycosis fungoides.

Florone is a topical ointment that contains 0.5mg of Florone. Florone ointment 0.05% is available in 15, 30 and 60 gram tubes,.

Certain side effects may result from the usage of Florone. The following side effects and reactions may be experienced with other corticosteroids. Stop using the ointment if severe inflammation, reaction and irritation is experienced using the ointment. Mood changes, weight gain, sleeplessness, and blurred vision may be one of the many major side effects of using Florone.

The lesser side effects may include mild reactions to the skin like rashes, dryness, pruritus, swelling, and thinning. The skin treated with Florone may also change color, as hair follicles may also swell up.

There are no known contraindicated medicaments with Florone; however, topical corticosteroids are known to be contraindicated in affected roles with a history of hypersensitivity to the ingredients of the ointment.

Once irritation to the skin has formed, discontinue the use of Florone and seek emergency medical care. In the case of skin infections, appropriate dermatological agents should be used (anti-fungal or antibacterial cream) alongside the Florone. If the condition is not alleviated, Florone use should be stopped until the skin infection is completely healed.

Reports have stated that absorption of topical corticosteroids over time may produce reversible HPA or hypothalamic-pituitary-adrenal axis suppression. It may also produce hyperglycemia and even glucosaria in some affected roles. This may be caused by application of dosages higher than required or prolonged usage of the medicament.

Children are reported to absorb larger amounts of these corticosteroid ointments and are more susceptible to systemic toxicity.

HPA suppression and other complications like Cushing’s syndrome and intracranial hypertension have been reported as cases in pediatric affected roles receiving topical corticosteroids. Manifestations of these diseases include retarded linear growth, delay in weight gain, low-level plasma cortisols, and the irresponsiveness to ACTH stimulation for adrenal suppression. Intracranial hypertension is manifested in affected roles with bulging fontanelles, bilateral papilledema and headaches.

Administering topical corticosteroids like Florone to pediatric affected roles should then be limited to the minimum amount coupled with effective therapy. The chronic use of Florone and other corticosteroids may interfere with the growth and development of children.

Florone has the following structural formula:

Chemical structure of Florone

• Molecular formula of Florone is C26H32F2O7
• Chemical IUPAC Name is [17-(2-acetyloxyacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8, 11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate
• Molecular weight is 494.525 g/mol

Generic name: Diflorasone

Brand name(s): Maxiflor, Psorcon

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