Fluvastatin review

Fluvastatin is a type of statin drug that is effective in the lowering of cholesterol. It is prescribed for the prevention of heart attacks and strokes.

Fluvastatin is known by the brand name Lescol. It is prescribed to individuals who need to lower their cholesterol levels and prevent the risk of heart ailments. Fluvastatin is prescribed only if other non-drug options such as change in diet, regular exercise, and weight loss fail to lower cholesterol levels.

Usually, physicians prescribe an initial intake of 40 milligrams of Fluvastatin every evening. This can be increased up to 80 mg per day. Physicians may also prescribe that patients take the drug twice a day. However, dosage may vary according to the condition of the patient.

Fluvastatin can be taken on an empty stomach. Those who take other medications for lowering of cholesterol such as colestipol will have to take Fluvastatin a couple of hours after taking their medications.

Patients have to use Fluvastatin regularly so they can get the full benefits of the medication. Patients may take the drug at the same time every day so they won’t forget taking Fluvastatin.

It usually takes a month before patients experience the full effects of Fluvastatin.

The most common side effects among users of Fluvastatin are upset stomach and muscle problems. Patients should immediately inform their doctors if they develop these symptoms, as well as muscle pain and weakness, and frequent or infrequent urination.

Other side effects which may happen, although highly unlikely, are yellowed skin and eyes, dark urine, extreme fatigue, abdominal or stomach pain, and nausea.

It is rare that patients suffer from allergic reaction to this medication. However they should seek medical help immediately if they experience rashes, itching, dizziness, difficulty in breathing, and swelling.

Before agreeing to take Fluvastatin, patients should tell their doctors or pharmacists if they have any allergic to drugs such as ‘statins’. Fluvastatin may also interact negatively with other medications such as anti-ulcer drugs, blood thinners, and anti-diabetes medications.

Patients should also inform their doctors of their medical condition, particularly those who have active liver ailment. Physicians also need to look at the medical history of the patient such as any history of liver and kidney disease, and alcohol abuse.

Patients should also inform their surgeon or dentist if they are taking Fluvastatin if they are to undergo surgery. They should limit their intake of alcohol as it can increase the risk of severe side effects.

The use of Fluvastatin among the elderly should be done with precaution since they are more at risk of serious side effects of the medication, particularly muscle damage.

Fluvastatin should never be used by pregnant women. Those who are planning to get pregnant should divulge their plans to their physician first before agreeing to take this medication.

There is also a risk that Fluvastatin is passed into infants through breastfeeding. Doctors do not recommend breastfeeding mothers to take Fluvastatin. In case Fluvastatin is needed, patients may have to stop breastfeeding while using the medication.

Fluvastatin has the following structural formula:

Chemical structure of fluvastatin

• Molecular formula of fluvastatin is C24H26FNO4
• Chemical IUPAC Name is 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-hept-6-enoicacid
• Molecular weight is 411.466 g/mol
Fluvastatin available : 20mg capsules, 40mg capsules and 80mg capsules

Brand name(s): Cranoc, Fluindostatin, Fluvastatina, Fluvastatine, Fluvastatinum, Lescol

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