Fosamax, which is generically prescribed as alendronate, is commonly used to treat osteoporosis in post menopausal women. Fosamax is a member of the family of drugs known as biophosphonates, which breaks the cycle of bone mass break down and loss in the body.
Fosamax is not appropriate for everyone. A thorough medical history should be assessed prior to prescribing this medication. Patients with a medical history which includes kidney disease, low blood calcium, vitamin D deficiency, or a stomach or esophagus ulcer may not be able to take Fosamax or may require careful monitoring while undergoing drug therapy with this medication, depending on the condition and the severity of the condition.
The American Food and Drug Administration rated Fosamax as a pregnancy risk category C. Fosamax may cause harm or birth defects to an unborn baby. It has yet to be determined whether or not this medication passes through the mother’s breast milk and affects a nursing baby. The prescribing physician should avoid prescribing Fosamax to a woman who is nursing and should thoroughly discuss whether the benefits outweigh the risks before prescribing this medication to a woman who is pregnant or has a high likelihood of becoming pregnant.
There is a risk of side effects associated with Fosamax, some of which are severe. A patient who is experiencing a serious side effect or an allergic reaction should seek immediate emergency medical attention. An allergic reaction will present with side effects such as facial swelling, including swelling of the lips, mouth, throat, or tongue, hives, and difficulty breathing. Other serious side effects which require immediate emergency medical attention include symptoms such as chest pain, difficulty swallowing, pain when swallowing, new or worsening heartburn, severe pain of the joints, severe bone or muscle pain, jaw pain or numbness or swelling of the jaw, and pain or burning under the ribcage.
Less serious side effects typically do not require emergency medical attention but should be reported to the prescribing physician. Patients should be encouraged to report all side effects. Less serious side effects include symptoms such as back pain, dizziness, weakness, headaches, diarrhea, gas, constipation, mild heartburn or stomach discomfort, joint pain, swelling of the joints, or swelling of the hands and feet. Less serious side effects can often be reduced to a tolerable level by reducing the dosage of Fosamax.
Fosamax should be taken exactly as it has been prescribed by the physician. If the patient misses a dose, the dose should be taken as soon as it is remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped to avoid the potential for an overdose. The patient should never take a double dose of this medication. If an overdose is suspected, the patient should seek immediate emergency medical attention. An overdose will present with symptoms such as tightness of the facial muscles, nausea, vomiting, numbness or tingling, irritability, unusual thoughts, unusual behavior, muscle cramps, stomach pain, diarrhea, or heart burn.
There is a potential risk of negative drug interactions associated with Fosamax. A thorough medical history should be understood prior to prescribing this medication. Patients should be urged to inquire with the prescribing physician before taking any new medications, including over the counter medications and herbal remedies. Medications with a known negative drug interactions with Fosamax include celecoxib, ibuprofen, Naproxen, piroxicam, ketorolac, or other NSAID pain relievers. Patients should not take any additional medication for thirty minutes after taking Fosamax, including over the counter vitamins and herbal remedies.
Fosamax has the following structural formula:
• Molecular formula of fosamax is C4H13NO7P2
• Chemical IUPAC Name is (4-amino-1-hydroxy-1-phosphono-butyl)phosphonic acid
• Molecular weight is 249.096 g/mol
• Fosamax available : 70mg/75ml solution 75ml bottle, 1 package = 4 tablets (35mg), 1 package = 4 tablets (70mg), 5mg tablets, 10mg tablets
Generic name: Alendronate
Brand name(s): Acide Alendronique, Acido Alendronico, Acidum Alendronicum, Adronat, Alendronate Sodium, Alendronic acid, Alendros, Arendal, Onclast
Review published on: 10 April 2007
 Your Fosamax review
| .: Add date: 2007-07-24 03:37:40 |
.: Score: 1 |
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I would give it a negative score if I could by 100 or more! My mother took it for 7 weeks, 70 mg., for pre-osteo and further prevention and was very healthy and active. She stopped taking it after 7 weeks/doses. She works full-time and hasn't had any pain prior. Now she cannot bend over or drive and has severe bone, muscle and joint aches. Her doctor encouraged her to continue although she complained after her second dose, second week. Her symptoms are worsening rather than improving. Is there a way to detox to pull the drug out of her system? How long can she expect the pain to continue? Is this a permanent condition?
Added by Nancy
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| .: Add date: 2007-08-17 19:25:14 |
.: Score: 10 |
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Took Fosamax more than six month, Dr. did not believe complaints of heartburn, muscle aches & cramps, backaches, runny nose, constipation plus general unwell feeling. Finally a specialist took pics of my esophagus (outpatient) found a hole & several sores. On my own I quitt taking Fosamax. Since then an orthodontal surgeon diagnosed jawdeath and no dental stents could be implanted ever. There is no cure & is caused by Fosamax. Think I'll be looking for another primary Dr.
Added by Gisela K. Toledo, OH
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| .: Add date: 2008-01-16 06:37:04 |
.: Score: 1 |
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I now have severe spine pain which I did not have before taking this drug
Added by robin
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| .: Add date: 2008-01-20 13:37:09 |
.: Score: 10 |
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I took Fosamax for ten months. My health is distroyed. I had painful swallowing and immediatly reported it to my doctor and she just chuckled. I also have constant heartburn. I have extreme pain in my spine. My dentist will not do an extraction or root canal. My dentist is also having me take a cancer screening of my mouth/jaw. I was in excellent health before I took Fosamax. I no longer trust doctors and hate the pharmacitical companies. Is this part of population control?
Added by annette
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| .: Add date: 2008-01-25 14:43:04 |
.: Score: 1 |
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took 2 doses actonel 2 years ago and was surprized when a tooth chiped with no trauma or decay. dr. persuaded me to try fosamax took 1 dose and have spine hip pain doctors are crooked
Added by catherine
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| .: Add date: 2008-02-12 08:13:14 |
.: Score: 5 |
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Anyone else experiencing urinary track infections since taking Fosamax? I had the same reaction to Boniva. Only Actonel seemed to work best w/o side effects.
Added by Marge
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| .: Add date: 2008-03-30 07:17:42 |
.: Score: 1 |
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After taking only one dose of Fosamax, I experiences muscle and joint pain I did not attribute that to the medicine until the second dosage. I called my doctor and was told to continue taking the medicine after the symptoms disappear. The doctor claimed they had never heard of these side effects and assumed it was something else. It's been a year, the symptoms have not disappeared. My quality of life is not the same. I hurt with every step. My joints and muscles hurt. I am not confident in my doctor nor the drug companies. I wish there was a cure but I'm sure they would give more drugs and who knows the results of them.
Added by Sue
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