Furazolidone review

Furazolidone kills bacteria and one-celled organisms called protozoa. By killing these parasites, Furazolidone effectively prevents the growth of various bacterial infections.

Furazolidone comes in oral suspension and tablet forms. It is popularly marketed as Furoxone in the United States.

Furazolidone is administered orally to patients of cholera, diarrhea, colitis, and giardiasis. It can also be given to complement other drugs for the treatment of bacterial infections.

It can be administered to adults and children, although babies who are under 1 month may not be fit to take this medication.

The dosage of Furazolidone may vary according to the age, weight, and condition of the patient.

For cholera or diarrhea resulting from bacterial infection, the usual dosage for adults is 100 milligrams administered four times a day. This should be taken for 5-7 days.

For children, the dosage may vary according to the body weight of the patient. Usually, the dosage is 1.25 milligrams for every 1 kilogram of body weight. This is taken four times a day from 5-7 days.

For those with giardiasis, the dosage for adults is 100 milligrams. This is taken four times a day from 5-7 days.

For children, the dosage depends on the body weight of the patient. Usually, the indicated dosage is up to 2 milligrams per kilogram of body weight. This is taken four times a day for 5-7 days.

In case of a missed dose, patients should immediately take the dose of Furazolidone. However patients should never take consecutive doses of this medication in order to make up for any missed dose.

Furazolidone may cause certain unwanted effects on its patients. Although the chances of side effects are relatively low, patients should seek medical attention if any of the side effects continue or worsen.

Rare side effects of the use of Furazolidone are fever, joint pain, itching, sore throat, redness, and skin rashes.

Less common side effects of Furazolidone are diarrhea, stomach pain, nausea, and headache.

Furazolidone may also result to patients having brown or dark yellow urine. This may not need any medical attention.

Patients are advised not to drink any alcoholic drinks while taking Furazolidone since it can lead to certain side effects like difficulty in breathing, redness of the face, and fainting.

Certain food and medicines can cause severe reactions like high blood pressure when taken while using Furazolidone. These include fermented food containing tyramine such as cheese, smoked meat, fish or poultry, fermented sausage such as salami and bologna, and overripe fruit.

Patients should also refrain from drinking large amounts of beverage containing large amounts of coffee like cola, tea, coffee, or chocolate.

Patients should tell their doctors their history of allergy to medicines like nitrofurantoin and nitrofurazone. They should also divulge information on their allergy to other substances such as dyes or preservatives.

Furazolidone, however, has not been proven to result to any birth defects among humans and animals even if they are given high doses for an extended amount of time.

Furazolidone has the following structural formula:

Chemical structure of furazolidone

• Molecular formula of furazolidone is C8H7N3O5
• Chemical IUPAC Name is 3-[(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
• Molecular weight is 225.1583 g/mol

Brand name(s): Bifuron, Corizium, Coryzium, Diafuron, Enterotoxon, Furall, Furaxon, Furaxone, Furazol, Furazolidine, Furazolidon, Furazon, Furidon, Furovag, Furox, Furoxal, Furoxane, Furoxon, Furoxone, Furozolidine, Giardil, Giarlam, Medaron, Neftin, Nicolen, Nifulidone, Nifuran, Nifurazolidone, Nitrofurazolidone, Nitrofurazolidonum, Nitrofuroxon, Optazol, Ortazol, Puradin, Roptazol, Sclaventerol, Tikofuran, Topazone, Trichofuron, Tricofuron, Tricoron, Trifurox, Viofuragyn

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