Glucobay review

Glucobay is a brand name for the generic medication acarbose. It is in a class of medications called alpha-glucosidase inhibitor, which means that it keeps the body from processing carbohydrates efficiently. This results in a smaller and more gradual release of blood sugar throughout the day. Glucobay is used in conjunction with diet to lower blood sugar in people who have type 2 diabetes mellitus, and who cannot control it with diet alone. Glucobay is given in pills and can also be used along with a sulfonylurea or with insulin when diet plus Glocobay is still not enough to keep blood sugar down.

Glucobay is not intended to work by itself. The first line of defense for the treatment of type 2 diabetes mellitus is always diet and lifestyle. In some severe cases, diet and lifestyle changes alone may not be enough to keep blood sugar controlled, so Glucobay is prescribed as a secondary, assisting measure. Glucobay is not to be used as a substitute for diet and exercise, but in addition to it.

Some people experience negative side effects when taking Glucobay. The most common of these are gastrointestinal symptoms such as abdominal pain, diarrhea, and flatulence. Most studies have shown that these symptoms tend to get better with time. These side effects will be much worse for those who are not following a prescribed diet and yet are still taking Glucobay. Other serious but rare effects include skin rash or hives, fatigue, weight loss or appetite loss, dark or brownish urine, or loss of appetite. You should also let your doctor know if you have hiatal hernia, kidney or liver disease, stomach or bowel disease, any kind of bowel obstruction, or allergies of any sort

Some drugs should not be taken at the same time as Glucobay. These drugs include thiazides or other diuretics, oral contraceptives, thyroid treatments, estrogens, phenytoin, sympathomimetics, nicotinic acid, calcium channel blockers, and isoniazid. If you do take these drugs at the same time as Glucobay, you should be monitored carefully to make sure your blood sugar doesn’t become uncontrolled. If you are receiving sulfonylureas or insulin at the same time as Glucobay, you may find that your blood sugar is too low, which could in extreme cases lead to hypoglycemic shock. It has also been shown that intestinal absorbents such as charcoal may reduce the effect of Glucobay. If you’re taking digoxin along with Glucobay, your doctor may wish to reduce your dose of digoxin.

Glucobay is in Pregnancy Category B, which means that it is not known whether it is safe to take during pregnancy or not. Animal tests suggest that it is largely safe, but animal tests do not always predict the outcome accurately for humans, so Glocobay should be avoided by pregnant women. It is not yet known whether Glucobay is effective or safe in breast milk, but studies indicate that it does pass into the mother’s milk. Therefore, Glucobay should not be administered to nursing women. It has also not been evaluated for use in children.

Glucobay has the following structural formula:

Chemical structure of glucobay

• Molecular formula of glucobay is C25H45N3O16
• Chemical IUPAC Name is (2R,3R,4S,5R,6R)-5-[(2R,3R,4S,5R,6R)-5-[(2R,3R,4S,5R,6R)-3,4-dihydroxy-6-methyl-5- [[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-1-cyclohex-2-enyl]amino]oxan-2-yl]oxy- 3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol
• Molecular weight is 643.635 g/mol
Glucobay available : 50mg tablets, 100mg tablets

Generic name: Acarbose

Brand name(s): Prandase, Precose

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