is a combination drug of Glyburide
. It is prescribed as a management therapy for patients with type 2 diabetes
. For the most part, Glucovance is used for patients who do not have daily insulin
injections. This medicine therapy controls high blood
sugar levels in adult diabetics
. It is prescribed along with proper diet and regular exercise to effectively reduce the health risks that diabetes
Glucovance comes in tablet form. Initially, a low dose of 250mg once or twice a day is prescribed. Dosages may be increased according to your body’s reactions to the drug. If the initial treatment cannot control blood sugar levels effectively, your doctor may adjust your dose. The 500mg tablet of Glucovance must not be used if you are just starting with the treatment. A strong initial dose increases the risk of hypoglycemia
or low blood sugar levels.
Glucovance is advised to be taken with meals, one after breakfast and another after dinner. Make sure that you take the drug at about the same time each day so as not to make any misses. Missing a dose of Glucovance might impede its results. If you miss a dose, take it as soon as you remember. If it is too close before your next dose, drop the missed dose and just continue with your regular dosing schedule. Do not stop taking Glucovance even if you feel well. Glucovance is a maintenance drug that must be taken regularly unless the doctor advises you otherwise.
It is importantto note that your Glucovance dosage may be altered every once in a while depending on the results of your periodical lab tests. To measure the effectiveness of Glucovance, you will be required to have regular blood and kidney
Patients under Glucovance treatment must avoid taking alcoholic drinks. Alcohol lowers blood sugar levels, thus increases the risk for lactic acidosis.
Before taking Glucovance, it is important that you subject yourself for a check-up. The doctor must assess your need for the drug as well as your dangers with it. Discuss your medical history including any allergies
and other health conditions apart from diabetes.
Glucovance must be used with care in patients with heart
disease, and kidney disorders. Its use in pregnant and lactating women must also be closely supervised as it may pose certain risks to both the unborn and nursing babies. Glucovance must also be administered with care in older adults who have higher risks of becoming inflicted with lactic acidosis.
Glucovance causes certain side effects that may present discomfort. The most common ones include symptoms of coughs and cold, headache
pain, and diarrhea
. Those symptoms may disappear after a few days of regularly taking the drug. If your symptoms persist or worsen, call your doctor immediately. You must also seek your doctor’s advice in case you suffer from less common but serious side effects of Glucovance such as breathing difficulty and rapid weight gain. You must also check yourself for any signs of allergic reactions
, which include swelling
Glucovance has the following structural formula:
• Molecular formula of glucovance is C23H28ClN3O5S
• Chemical IUPAC Name is 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
• Glucovance available : 1.25 mg glyburide with 250 mg metformin tablets, 2.5 mg glyburide with 500 mg metformin tablets and 5 mg glyburide with 500 mg metformin
Generic name: Glibenclamide
Brand name(s): Abbenclamide, Adiab, Azuglucon, Bastiverit, Benclamin, Betanase, Calabren, Cytagon, Daonil, Debtan, Dia-basan, Diabeta, Diabiphage, Dibelet, Duraglucon, Euclamin, Euglucan, Euglucon, Euglykon, Gewaglucon, Gilemal, Glamide, Glibadone, Gliban, Gliben, Glibenbeta, Glibenclamida, Glibenclamidum, Glibenil, Glibens, Glibesyn, Glibet, Glibetic, Glibil, Gliboral, Glicem, Glidiabet, Glimel, Glimide, Glimidstata, Glisulin, Glitisol, Glubate, Gluben, Gluco-Tablimen, Glucobene, Glucohexal, Glucolon, Glucomid, Glucoremed, Glucoven, Glyben, Glybenclamide, Glybenzcyclamide, Glyburide, Glycolande, Glycomin, Glynase, Hexaglucon, Humedia, Lederglib, Libanil, Lisaglucon, Malix, Maninil, Med-Glionil, Melix, Micronase, Miglucan, Nadib, Neogluconin, Norglicem 5, Normoglucon, Novo-Glyburide, Orabetic, Pira, Praeciglucon, PresTab, Prodiabet, Renabetic, Semi-Daonil, Sugril, Suraben, Tiabet, Yuglucon