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Haloperidol

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Haloperidol

Haloperidol review





Haloperidol is a very powerful antipsychotic drug that has been found effective for managing conditions like agitation, hyperactivity and mania. It is also an effective treatment for patients diagnosed with schizophrenia.

It has also been found as an effective treatment for psychosis and other forms of hallucination. It is even prescribed as treatment for patients experiencing psychosis as a result of drug use.

Approved by the Food and Drug Authority in 1967, Haloperidol is also prescribed to patients with Gilles de la Tourette’s syndrome. Haloperidol helps manage the tics and vocal utterances common to Tourette’s syndrome.

Haloperidol is also applicable to children who display severe problems in their behavior. Haloperidol can be prescribed to children who have extremely combative and explosive behavior or temperament. Haloperidol can also address hyper excitability.

Basically, Haloperidol works by interfering with the neurotransmitters in the brain. Neurotransmitters are chemicals that carry signals between and across various nerves in the brain. By interfering with the functions of the neurotransmitter, Haloperidol is able to deactivate certain signals and functions that lead to uncontrolled and excessive movements in the body, such as tics.

Haloperidol can be taken orally. It can also be given via intramuscular or intravenous injections. The dosage for Haloperidol varies greatly depending on the condition of the patient. Usually, if the symptoms pf psychotic illnesses or any other syndrome can no longer be easily managed, Haloperidol is given in higher doses and is administered more frequently.

Because Haloperidol is extremely powerful, very strict precaution must be taken before it is taken by a patient.

First of all, if a patient has ever been in a state of comatose or has ever experienced severe stroke, he cannot be allowed to take Haloperidol. People who are currently addicted to alcohol or to illegal substances will also be prevented from taking Haloperidol.

Meanwhile, people who have Parkinson’s disease can take Haloperidol but with great caution. Patients with epilepsy must also take great care when using Haloperidol. Since Haloperidol is metabolized in the liver, patients with liver injury should also be careful.

Pregnant women are also discouraged from taking Haloperidol since it poses significant risk of deformities in the fetus. Breastfeeding is also not encouraged since Haloperidol passes through the milk. Children who breastfed on mothers taking Haloperidol are often observed with side effects attributed to actually drinking Haloperidol.

Haloperidol is also known to cause extrapyramidal side effects during the early and late parts of the treatment period.

These extrapyramidal side effects are basically physical reactions to antipsychotic medications. This can include tremors, slurred speech, paranoia, anxiety and distress. The patient may also experience restlessness where he may even be unable to sit still. The patient may also feel involuntary muscle contractions or spasms that may be accompanied with pain. In some cases, the patient may experience bradyphrenia, a condition where the patient’s thought process becomes much, much slower as a result of the drug’s effect on the brain. Dry mouth and lethargy are also common side effects.

In some cases where the treatment is prolonged, Haloperidol may lead a patient to develop severe depression, almost to a suicidal extent.

In extreme situations, antipsychotic drugs like Haloperidol can lead to a rare but fatal condition termed as neuroleptic malignant syndrome (NMS). NMS is often manifested through symptoms such as delirium, fever and muscle rigidity.

Haloperidol has the following structural formula:

Chemical structure of haloperidol


• Molecular formula of haloperidol is C21H23ClFNO2
• Chemical IUPAC Name is 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one
• Molecular weight is 375.864 g/mol
Haloperidol available : 0.5mg tablets, 1mg tablets, 2mg tablets, 5mg tablets, 10mg tablets, 20mg tablets

Brand name(s): Aloperidin, Aloperidol, Aloperidolo, Aloperidon, Apo-Haloperidol, Bioperidolo, Brotopon, Dozic, Dozix, Einalon S, Eukystol, Galoperidol, Haldol, Haldol Decanoate, Haldol La, Haldol Solutab, Halidol, Halojust, Halol, Halopal, Haloperido, Haloperidol Decanoate, Haloperidol Intensol, Haloperidol Lactate, Halopidol, Halopoidol, Halosten, Keselan, Lealgin Compositum, Linton, Mixidol, Novo-Peridol, Pekuces, Peluces, Peridol, Pernox, Pms Haloperidol, Serenace, Serenase, Serenelfi, Sernas, Sernel, Sigaperidol, Ulcolind, Uliolind, Vesalium

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