can often be shortened to just HCT, HCTZ, or HZT so that patients and doctors don’t have a hard time remembering it. HCT is a complicated drug that is used mainly for heart
problems, high blood pressure
, symptomatic edema and the prevention of kidney stones
. Basically what this drug does is act on the kidneys
so that sodium is reduced throughout the body and less water is retained in the kidneys. This decreases the pressure on the kidneys; and this also decreases blood
flow to the heart, thus relieving it of pressure. This is a diuretic drug that mainly affects the heart and the kidneys, and it usually regulates the amount of sodium in both organs.
One of the main effects of the drug is to increase the frequency of urination
. This is because the drug actually stops your body from keeping sodium and water in your body, instead all the sodium and water is urinated out. Due to this effect Hydrochlorothiazide can be used effectively against nephrogenic diabetes insipidus
, which is a disease that keeps you from urinating.
Some common side effects are hypomagnesemia, gout
, and hypokalemia
, which can be treated with a potassium-sparing diuretic. All these side effects can be treated with simple supplements and drugs. More common side effects are high blood sugar, high cholesterol, headaches
, muscle weakness, muscle pain
, sensitivity to sunlight, nausea
. Some serious side effects include rashes, hives
of the throat and face, and difficulty breathing. If any of these side effects occur see a doctor immediately.
Before taking Hydrochlorothiazide inform your doctor if you are taking any drugs that might interfere with the treatment. The treating physician should know about drugs for high blood pressure, holestyramine such as Prevalite, colestipol
, anti-inflammatory medications like ibuprofen
, steroids, lithium, medications for diabetes
, and any other over the counter or prescription medication. Your doctor might want to change the dose if he learns you are on a drug that might interfere with Hydrochlorothiazide.
It is also important to inform your doctor if you have had diabetes, gout, and liver
or thyroid diseases. These diseases hurt the organs that might be affected by Hydrochlorothiazide and they might react badly to the drug if they are delicate. This drug hasn’t been cleared for use by pregnant women, so if you are pregnant or become pregnant during the course of treatment please inform your doctor. Nursing mothers should also note that Hydrochlorothiazide is passed on through breast
milk, so they should discontinue nursing while on this treatment.
Hydrochlorothiazide is sold generically and under the brand names Dichlotride, Hydrodiuril, Microzide
, and Oretic. The pills come in many varying doses depending on the brand, and they include 10 mg up to 100 mg tablets. They are often light colored and round tablets that vary in color according to brand. This drug is usually taken twice a day with meals. A helpful tip is to change your diet to a potassium-rich diet while you are on this drug. It also helps to keep your sodium intake low, following these tips will help the drug do its work faster and hopefully the effects will last longer as well.
Hydrochlorothiazide has the following structural formula:
• Molecular formula of hydrochlorothiazide is C7H8ClN3O4S2
• Chemical IUPAC Name is 9-chloro-5,5-dioxo-5^6-thia-2,4-diazabicyclo[4.4.0]deca-6,8,10-triene-8-sulfonamide
• Molecular weight is 297.741 g/mol
• Hydrochlorothiazide available : 12,5mg capsules, 25mg tablets, 50mg tablets
Brand name(s): Acuretic, Aldactazide, Aldoril, Apresazide, Aquarills, Aquarius, Bremil, Caplaril, Capozide, Chlorosulthiadil, Chlorothiazide, Chlorzide, Cidrex, Dichlorosal, Dichlorotride, Dichlotiazid, Dichlotride, Diclotride, Dicyclotride, Dihydrochlorothiazid, Dihydrochlorothiazide, Dihydrochlorothiazidum, Dihydrochlorurit, Dihydrochlorurite, Dihydroxychlorothiazidum, Direma, Disalunil, Diu-Melusin, Diuril, Drenol, Dyazide, Esidrex, Esidrix, Esimil, Fluvin, Hidril, Hidrochlortiazid, Hidroronol, Hidrotiazida, Hydril, Hydrochlorothiazid, Hydrodiuretic, Hydrodiuril, Hydropres, Hydrosaluric, Hydrothide, Hydrozide, Hypothiazid, Hypothiazide, Hyzaar, Idrotiazide, Inderide, Ivaugan, Maschitt, Maxzide, Megadiuril, Microzide, Moduretic, Nefrix, Neo-Codema, Neoflumen, Newtolide, Oretic, Palonyl, Panurin, Perovex, Primogyn, Prinzide, Ro-Hydrazide, Servithiazid, Thiaretic, Thiuretic, Thlaretic, Timolide, Unipres, Urodiazin, Vaseretic, Vetidrex, Ziac, Zide