Imipramine review

Imipramine is an antidepressant drug that was discovered and developed in the 1950s. During that time, tricyclic antidepressants are the order of the day and Imipramine is one of the most popular. It was first tried against Schizophrenia and other psychotic disorders but its real strength turned out to be in battling depressive episodes. Through the years, Imipramine’s ability to elate even the ugliest slump is unsurpassed. Thus, it remains one of the most trusted antidepressant drugs ever. However, with the introduction of SSRI or Selective Serotonin Reuptake Inhibitor drugs, Imipramine’s side effects are brought to the spotlight. That is why doctors and experts alike preferred to use it only as a second line of treatment nowadays.

Aside from treating clinical depression, Imipramine is also useful in relieving patients, especially children five years and above, of Urinary Incontinence. Before treatment, patients are worked up to undergo several clinical tests and physical examinations to ensure that organic dangers are out of the picture. Whether it is to be used in adult or children, an Imipramine treatment must not be given a go signal unless it was brought to a doctor’s attention.

An Imipramine treatment must be based upon correct diagnosis and careful review of a patient’s current physical condition. It cannot be given based on the patient’s symptoms alone. Like other drugs, the use of Imipramine has contraindications and precautions. For one, it should not be given simultaneously with a MAO or monoamine oxidase inhibitor drug. It is also not advisable to be used by patients with glaucoma, hypertension, renal disease, and allergy to tricyclic antidepressants especially those under the dibenzazepine group.

Imipramine is taken orally by the mouth. It comes in tablet and capsule forms that are usually prescribed once to twice daily. The dose is usually started low and is increased gradually. Imipramine is a long-acting drug. It may take a little while before a patient recognizes its full potential. The dosage requirement and schedule of a patient depends on his level of affliction. As such, no two patients must share a single prescription without a proper consultation with a doctor. Diagnosis is always a case-to-case basis and it is the only source of a doctor’s prescription.

There is a common risk in taking tricyclic antidepressants that is also present with Imipramine. That risk concerns a patient’s suicidal tendencies. Experts are still in the process of finding out to what extent does an antidepressant encourages suicidal acts. Still, you must keep this in mind before taking an Imipramine prescription.

Imipramine also causes several mild conditions that usually appear because your body is not adjusted to the drug yet. Mild episodes of nausea, drowsiness, dry mouth, urination problems, blurred vision, dry mouth, and changes in your mental health are but normal. However, if they become bothersome or went beyond the bearable level, call your doctor immediately. Since the threats of Imipramine are anything but simple, make sure that you are under competent supervision while using the drug. Any side effect that overpowers the benefits that you are getting from Imipramine requires serious medical attention. Your caregiver or anyone from your family must know that.

Imipramine has the following structural formula:

Chemical structure of imipramine

• Molecular formula of imipramine is C19H24N2
• Molecular weight is 280.407 g/mol
Imipramine available : 10mg tablets, 25mg tablets, 50mg tablets

Brand name(s): Antideprin, Apo-Imipramine, Berkomine, Censtim, Censtin, Declomipramine, Dimipressin, Dyna-Zina, Dynaprin, Estraldine, Eupramin, Imavate, Imidobenzyle, Imipramina, Imiprin, Imizin, Imizine, Imizinum, Impramine, Impril, Intalpram, Iramil, Irmin, Janimine, Melipramin, Melipramine, Nelipramin, Norfranil, Novopramine, Pramine, Prazepine, Presamine, Promiben, Psychoforin, Surmontil, Surplix, Timolet, Tipramine, Tofranil, Tofraniln A

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