Kefral review

Kefral is a second-generation broad-spectrum antibiotic from the antibacterial medications known as cephalosporins. It is available by the brand names Ceclor, Ceclor CD, Ceclor Pulvules, and Raniclor.

Kefral is used to treat bacterial infections like pneumonia, and infections of the ear, lung, skin, throat, and urinary tract. It works by penetrating the body’s tissues and fluids, and obstructing the growth of the bacteria causing the infection.

Patients should avoid Kefral if they are allergic to cephalosporin, penicillin or other antibiotics. If they have a kidney disorder or any digestive disease like colitis, patients should inform their physician of these illnesses and get a prescription for a different dosage and be monitored during the course of treatment.

In the suspension liquid, Kefral contains sucrose, which is not advisable for diabetics. Pregnant women or those planning to become pregnant should talk with their physician before treatment. Since Kefral can be passed on through breast milk, nursing mothers need to tell their physician if they are breastfeeding before taking any of the medication, so as not to affect nursing infants.

Patients should not take antacids that contain magnesium or aluminum while taking Kefral as these can lower the efficacy of the antibiotic. Some antacids to avoid are Rolaids, Maalox, Mylanta, and Milk of Magnesia. Other medications known to interact with Kefral include Warfarin (an anticoagulant), Probenecid (an arthritis and gout medication), loop diuretics or water pills, and other antibiotics. Patients should inform their physician of any medications, vitamins or herbal supplements they are taking prior to starting Kefral treatment.

Known side effects include allergic reactions in the form of rashes, itching, uticaria (hives), fever, serum sickness-like reactions (hypersensitivity), arthralgia (joint pain), and anaphylaxis (whole body allergy). Some patients may experience diarrhea, nausea, vomiting, stomach upset, transient hepatitis, jaundice, headaches and Stevens-Johnson syndrome (a deadly allergic skin disease). In rare cases, blood disorders, nephritis (kidney inflammation), hyperactivity, nervousness, disrupted sleep, hallucinations, confusion and dizziness have occurred.

Patients should stop taking Kefral and seek emergency medical attention if they experience severe allergic reactions including breathing difficulties, swelling of the facial tissue, rashes, redness or itching, nausea, vomiting or diarrhea, blood or mucus in their stools, or unexplained bleeding and bruising. Any side effect experienced by the patient should be reported to their physician, particularly if it interferes with day-to-day activities.

Kefral is available in purple and white 250 mg. capsules, purple and gray 500 mg. capsules, and as a suspension (liquid) in strawberry flavor. Ceclor CD is manufactured in blue tables of 375 and 500 mgs. When taking Kefral in liquid suspension, the bottle needs to be shaken and the correct dosage accurately measured using a measuring spoon or cup.

Kefral is to be taken with a full glass of water on a full or empty stomach. Ceclor CD, in extended release capsules, should be taken with food or milk to prevent an upset stomach. Ceclor CD tablets are made so the medicine is released slowly into the body, so it is advisable not to cut, grind or chew them.

While symptoms of an infection often disappear quickly, the bacteria causing the infection may still remain in the body. Cutting the medication process short may cause the body to develop a resistance to the antibiotics.

Kefral needs to be taken regularly for the prescribed period to make sure the body maintains a consistent level of the medication, and to obtain the best results. Any unused medication should be disposed of after 14 days.

Kefral has the following structural formula:

Chemical structure of kefral

• Molecular formula of kefral is C15H14ClN3O4S
• Chemical IUPAC Name is (6R,7R)-7-[(2-amino-2-phenylacetyl)amino]-3-chloro-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Molecular weight is 367.8074 g/mol
Kefral available : 250mg capsules, 500mg capsules, 187mg/5ml suspension 100ml bottle, 375mg/5ml suspension 100ml bottle, 125mg/5ml suspension 150ml bottle, 250mg/5ml suspension 150ml bottle, 187mg/5ml suspension 50ml bottle, 375mg/5ml suspension 50ml bottle, 125mg/5ml suspension 75ml bottle, 250mg/5ml suspension 75ml bottle

Generic name: Cefaclor

Brand name(s): Alenfral, Alfacet, Alfatil, Ceclor, Ceclor CD, Cefaclorum, Cephaclor, Distaclor, Panacef, Panoral, Raniclor

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