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Kemstro

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Kemstro

Kemstro review





Kemstro is the generic name of a medication used for conditions affecting the central nervous system like spinal cord injuries, spastic diplegia (a type of cerebral palsy), encephalomyelitis disseminata (a chronic inflammatory disease of the nervous system), amyotrophic lateral sclerosis (Lou Gehrig's Disease), and trigeminal neuralgia (a painful neuropathic disorder affecting the facial muscles).

Kemstro is derived from gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitters in the central nervous system. It contains substances that bind themselves to GABA receptors to decrease nerve activity in the area of the brain that controls the skeletal muscles. It is an anti-spastic agent and muscle relaxant used to loosen up skeletal muscles and prevent spastic and convulsive movements stemming from disorders of the nervous system.

Kemstro is absorbed very quickly and dispersed throughout the body. It acts on the nerves of the spinal cord, eases muscle stiffness, and enables the muscles to move more easily and with less pain. It is also used in the treatment of hiccups. Before starting Kemstro treatment, inform your doctor if you are allergic to Kemstro, or any other medications, including other muscle relaxants, sleeping pills or tranquilizers. Your doctor also needs to know if you have had kidney disease, epilepsy, a history of stroke or blood clots, rheumatic disease, ulcers, cerebral palsy, diabetes, Parkinson's disease or any kind of psychiatric disorders. Any of these conditions may warrant a dose adjustment and frequent medical monitoring while taking Kemstro. Also make certain that your doctor is aware of any prescription or over-the-counter medications you may be taking, including any vitamin, mineral or herbal products, as any of these can react adversely with Kemstro.

Using Kemstro with tricyclic antidepressant medications like Elavil and Sinequan can reduce brain functions and may cause weakened muscles. Baclofan should not be taken with monoamine oxidase inhibitors like Nardil and Parnate to avoid further loss of brain functions as well as low blood pressure.

Kemstro, classified by the FDA as pregnancy category C, may harm an unborn baby. Patients are advised to inform their doctor if they are pregnant or plan to become pregnant during the course of treatment. Kemstro may pass into breast milk and harm a nursing infant, so it is important not to administer the medication to a mother who is breastfeeding.

Kemstro also causes sleepiness, impairs judgment, decreases alertness, and causes muscle weakness. Patients taking this medication should avoid driving, operating any kind of machinery, or consuming alcoholic beverages, which can exacerbate these conditions.

Known side effects include drowsiness, dizziness, headaches, weak muscles, some nausea, constipation, and increased urination. However, if the patient starts having breathing difficulties, hives, facial swelling, confusion and hallucinations, uneven heartbeat and even seizures, seek emergency medical attention as these are signs of a severe allergic reaction to Kemstro. Kemstro is available with prescription under its generic form or under the brand names Lioresal and Kemstro. It comes in 10 to 20 mg tablets, and in a liquid solution (0.05mg/ml, 10 mg/5 ml and 10 mg/20 ml) that can be taken orally or intrathecally (injected into the spinal fluid) for patients with severe and painful spasms.

Kemstro should be taken exactly as prescribed by the doctor, usually 5 mg three times a day, with or without food, as a starting dose for adults. Patients are advised to continue taking Kemstro even after symptoms have decreased or ceased. Suddenly stopping without the doctor's advice can cause withdrawal symptoms like seizures or hallucinations, high fever, increased muscle spasms and convulsions, a breakdown of the muscles, organ failure, and even death. Doctors will usually recommend a gradual decrease of medication before completely stopping Kemstro treatment.

Kemstro is currently under research for use in minimizing the side effects of alcohol and opium withdrawal symptoms, and to help patients recover from substance abuse cravings (such as cocaine).

Kemstro has the following structural formula:

Chemical structure of kemstro


• Molecular formula of kemstro is C10H12ClNO2
• Chemical IUPAC Name is 4-amino-3-(4-chlorophenyl)-butanoic acid
• Molecular weight is 213.661 g/mol
Kemstro available : 10mg tablets, 20mg tablets

Generic name: Baclofen

Brand name(s): Baclon, Lioresal

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