Lamotrigine review

Lamotrigine is classified under a group of medications known as anticonvulsants (anti-epileptic drugs), which are prescribed for the management of seizure disorders. It may be used alone or in conjunction with other drugs to treat convulsions in adults and in children as young as 2 years old. Aside from controlling seizures, Lamotrigine is also used to put off mood swings in patients suffering from Bipolar Disorder.

Lamotrigine produces an effect on the central nervous system to keep the severity and frequency of seizures under control. It is believed to stifle the activity of specific brain segments, as well as the aberrant firing of seizure-causing nerve cells.

In order to induce the best possible outcome and to lessen the likelihood of untoward reactions, you should take Lamotrigine as prescribed by your physician. It may be taken with food or on an empty stomach. Then again, if your doctor tells you to take the medication in a particular way, stick to his/her instructions.

The dispersible/chewable tablets may be swallowed in one piece or chewed up. You may even dissolve the tablet in a small amount of fluid depending on your preference. Wait for about a minute until the medicine is completely dispersed before gulping it down.

Initially, patients who are not taking valproic acid is given 50 mg of Lamotrigine once daily for a period of two weeks. This dosage is subsequently increased to 100 mg per day in two divided doses for fourteen days. After that, the typical maintenance dose is 300-500 mg daily, still in two divided doses.

It is vital for your physician to check your progress with Lamotrigine therapy at regular appointments, particularly during the initial months of treatment. This will give him/her a chance to adjust your dosage, if needed. On top of that, the likelihood of experiencing unwanted effects will also be reduced.

If you’re a woman, you should not begin or discontinue the use of birth control pills and other hormonal supplements during the course of Lamotrigine treatment. You need to consult your doctor about it first. In case you experience abnormal changes in your menstrual cycle while taking birth control pills alongside Lamotrigine, report the incident to your doctor immediately.

Lamotrigine tends to boost the effects of CNS depressants and alcohol. Examples of depressant drugs include antihistamines, tranquilizers, sedatives, sleeping pills, pain medications, barbiturates, anticonvulsants, anesthetics, and muscle relaxants. Check with your physician before you take any of the previously mentioned drugs.

The use of Lamotrigine may bring about a number of side effects and adverse reactions. These unwanted effects include visual problems (double/blurred vision), unsteadiness, clumsiness, drowsiness, or dizziness. Ensure that you are aware of your own responses to this drug before you attempt to drive a car, operate a machine, or engage in any activity that could endanger you and/or other people. Check with your doctor if the reactions become excessively bothersome.

A skin rash could be a sign of a severe adverse reaction. Notify your doctor immediately if you develop one. Flu-like symptoms, fever, swollen glands or worsening seizure episodes also warrant prompt medical attention.

Lamotrigine has the following structural formula:

Chemical structure of lamotrigine

• Molecular formula of lamotrigine is C9H7Cl2N5
• Chemical IUPAC Name is 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
• Molecular weight is 256.091 g/mol
Lamotrigine available : 5mg tablets, 25mg tablets

Brand name(s): Lamictal, Lamictal Cd, Lamotrigina, Lamotriginum

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