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Latazanavir

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Latazanavir

Latazanavir review





Latazanavir, popularly known as Reyataz as marketed by Bristol Myers, is an antiretroviral medication used in the treatment of Human immunodeficiency virus. It is a protease inhibitor-type medication that can be used in conjunction with a variety of other medications in Human immunodeficiency virus treatment. Reyataz is available in 100mg, 150mg, 200mg and 300mg capsules. Latazanavir is unique because it can be used to treat Human immunodeficiency virus mutations that have grown immune to other forms of treatment and medications.

However, Latazanavir cannot cure Human immunodeficiency virus or prevent the spread of it. It also does not prevent other illnesss and infections, which may be acquired as a secondary effect of Human immunodeficiency virus.

Latazanavir can be given to patients 6 years old and older as part of a comprehensive Human immunodeficiency virus treatment program. It was approved by the Food and Drug Administration in 2003 as an antiretroviral (ARV) medication for Human immunodeficiency virus patients. When to start ARV treatment will depend on your doctor's analysis of your condition and reaction to current and previous treatments. Continual treatment with Latazanavir in conjunction with other ARVs can significantly lower viral load count and progressively improve the patient's health conditions.

Latazanavir is designed to be taken once a day with the recommended dose being 300 mg taken with 100 mg of ritonavir, another ARV medication. The ritonavir acts as a “booster” for the Latazanavir, but for patients who cannot take ritonavir for one reason or another, a 400 mg dose of Latazanavir may be recommended by your doctor.

Latazanavir should be taken regularly in order to prevent Human immunodeficiency virus levels from rising again, which may increase the risk for medication resistance. It is recommended to take Latazanavir with the same meal or snack everyday. Not only does this make it easier to take it regularly, the medication works better when taken with food.

Upon missing a dose, take the dose as soon as possible and take the next dose as originally scheduled unless it is too near the next dose when you remember. Do not double the dosage to make up for a skipped dose. Make sure any other accompanying medication is also taken properly and on time.

Dosage for children under 6 depends on their weight and medical history.

Common side effects of this medication include wamble and vomiting, diarrhea, stomachache, headaches, fever, dizziness and trouble sleeping. If these effects persist, consult your doctor.

Less common, more serious side effects of Latazanavir include arrhythmia, rashes which may be accompanied by swelling, flu-like symptoms and fever, and jaundice. Latazanavir may also cause and aggravate diabetes in some cases. Kidney stones may also develop and cause pain while passing urine, blood in urine and pains in the side. Gallstones and other gallbladder conditions have also been observed when taking the medication. Consult with your doctor immediately if any of these side effects occur.

Inform you doctor of any current or past hepatitis B or C infections, as well other liver disorders. Latazanavir may complicate these existing conditions. It is not currently known whether Latazanavir can be passed through breastmilk, but Human immunodeficiency virus can be so it is advisable to avoid breastfeeding. Those taking medication for blood pressure and heart conditions should also consult their doctors as Latazanavir may increase their effects.

Latazanavir has the following structural formula:

Chemical structure of latazanavir


• Molecular formula of latazanavir is C38H52N6O7
• Chemical IUPAC Name is methyl [1-[[3-hydroxy-4-[(2-methoxycarbonylamino-3,3-dimethyl-butanoyl) amino-[(4-pyridin-2-ylphenyl)methyl]amino]-1-phenyl-butan-2-yl] carbamoyl]-2,2-dimethyl-propyl]aminoformate
• Molecular weight is 704.856 g/mol
Latazanavir available : 100mg tablets, 150mg tablets, 200mg tablets and 300mg tablets

Generic name: Atazanavir

Brand name(s): Zrivada

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