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Levofloxacin

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Levofloxacin

Levofloxacin review





Levofloxacin is a third generation fluoroquinoline antibiotic. It is used to treat different gram-negative bacteria as well as gram-positive bacteria. Since Levofloxacin has a broad spectrum of action, it is mostly used as treatment even before the specific organism that has caused the infection is known. Once the causal organism has been specified, a new antibiotic specialized for that certain medicine can then replace Levofoxacin.

The gram-positive bacteria that Levofloxacin is effective against include enterococcus faecalis, staphylococcus saprophyticus, staphylococcus epidermidis, streptococcus pyogenes, streptococcus pneumoniae and staphylococcus aureus. As for gram-negative bacteria, Levofloxacin is effective against campylobacter, proteus mirabilis, haemophilus parainfluenzae, moraxella catarrhalis, haemophilus influenzae, serratia marcescens, legionella pneumophila, escherichia coli, pseudomonas aureginosa, klebsiella pneumoniae, and enterobacter cloacae.

Levofloxacin is sold in the form of tablets thus this drug is taken in per orem. It should be taken with a full glass of water. The usual dosage is once a day that could run for 1 to 2 weeks (7 to 14 days). For some infections, taking in of Levofloxacin may last for 6 weeks and sometimes longer in some cases. However, dosage will differ from patient to patient thus it is important to always follow the prescription label as well as the specific instructions of your physician. It is important to religiously follow the directions and always remember not to take more and not to take less of the prescribed dosage.

A common mistake of patients when taking Levofloxacin is that they tend to stop taking the medication as soon as they feel well. This should not be the case. Even if you feel better, you should continue taking the drug until the time to cease medication prescribed by your doctor has arrived.

Before taking Levofloxacin, there are some special precautions that you should know about. First, you need to inform your doctor whether you have any known allergies to Levofloxacin and its components. Not just that, you need to let your doctor know of any allergic reactions you have with food, preservatives, dyes and other medications.

Another information that your physician should know about is whether you are currently taking any kind of medications. This would include alternative medicines, herbal medicines, vitamins and nutritional supplements.

Your physician should also know whether you have any kind of liver or kidney condition. In the case of pregnant women or to those who plan to be pregnant, your doctor should also know about it too.

The most common side effects of Levofloxacin are nause and vomiting. Other common side effects include diarrhea, headache, and constipation. Other not-so-common side effects are abdominal pain, abdominal gas, itching, skin rashes, dizziness, and difficulty in sleeping.

A patient taking Levofloxacin may also experience difficulty in swallowing, difficulty in breathing, swelling of certain parts of the face, dark urine, blood in urine, painful tendons, irregular heartbeats and dark stools. These side effects however are quite rare. Although side effects are normal, any persistence of any of them should be reported as soon as possible to the doctor. This can help in the prevention of any complications in the future.

Levofloxacin has the following structural formula:

Chemical structure of levofloxacin


• Molecular formula of levofloxacin is C36H42F2N6O9
• Chemical IUPAC Name is (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- oxo-7Hpyrido[1,2,3-de]-1,4 benzoxazine-6-carboxylic acid hemihydrate
• Molecular weight is 740.751 g/mol
Levofloxacin available : 250mg tablets, 500mg tablets, 750mg tablets

Brand name(s): Cravit, Elequine, Floxel, Iquix, Leroxacin, Lesacin, Levaquin, Levokacin, Levox, Levoxacin, Mosardal, Nofaxin, Quixin, Reskuin, Tavanic, Volequin

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