Losartan review

Losartan is a kind of medication that is primarily given to patients with hypertension. However, it can also help people stop the progression of certain kidney problems. Losartan falls under the group called angiotensin II receptor antagonists.

By resisting the effects of Angiontensin II, Losartan produces two main effects. Firstly, it helps improve the blood flow by preventing certain chemicals from tightening the blood vessels. Secondly, it aids in the function of the kidneys, helping the body eliminate excess fluid. This also reduces the fluid in the blood vessels, thereby improving the blood’s ability to circulate. Combined, these effects work to lower the person’s blood pressure.

Losartan is normally offered as a tablet. Taken orally, Losartan must be administered either once or twice each day. It is also taken without food. The dosage will, of course, differ according to the patient’s condition. Hence, it is necessary to talk to your doctor about how you need to take Losartan.

It is also important that Losartan can only help regulate a perosn’s blood pressure. It cannot cure hypertension. As such, the person is advised to take Losartan regularly even though he may not feel ill that day. This way, your blood pressure is managed properly and you will prevent further complications in the future.

Since Losartan deals with fluids in the body, it is crucial that the patient undergo regular tests to ensure that there is a normal amount of potassium in the blood.

Also, Losartan must be taken with care especially if the patient is under some form of condition that leads to low volume of fluids in the body. This includes situations of diarrhea, vomiting, dialysis and diuretic therapy. More importantly, if the patient has an existing kidney condition, the intake of Losartan must be carefully monitored. This is especially true for those who are already experiencing some form of deterioration in the function of their kidneys. Also, those who have renal artery stenosis or have had kidney transplant should definitely talk to their doctor before considering Losartan as a form of treatment. People with existing liver or heart disease should also take some extra tests and evaluations to determine whether Losartan would be safe for them.

Also, pregnant women are discouraged from taking Losartan since it might affect the proper development of the fetus. Moreover, Losartan’s effect on the breast milk has not yet been determined. As a form of precaution, do stop taking Losartan if you are breastfeeding your child.

Depending on the person’s condition, Losartan will affect each person differently. However, there are certain side effects that seem to be common to most of the people who take Losartan. This would include diarrhea, migraine, fatigue and joint/muscle pain. There are also other effects related to Losartan’s effects to the body fluids. Patients may experience conditions like low blood pressure, high potassium content, and even anemia. In some cases, the liver may swell and its functions may decrease.

Losartan has the following structural formula:

Chemical structure of losartan

• Molecular formula of losartan is C22H23ClN6O
• Chemical IUPAC Name is [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]- 3H-imidazol-4-yl]methanol
• Molecular weight is 422.911 g/mol
Losartan available : 12.5mg tablets, 25mg tablets, 50mg tablets

Brand name(s): Cozaar, Hyzaar, Lacidipine, Lortaan

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