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Macladin

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Macladin

Macladin review





Antibiotics are classified into different groups based to their strength in tackling bacteria and the diseasees that come with them. While Cefixim and Cephalexin are included in the milder group of cephalosporin antibiotics, Macladin is in the stronger group of macrolide antibiotics. Macladin is found useful in severe cases of infections in the lungs (pneumonia), the tubes that lead to the lungs (bronchitis), and in the skin. It is even helpful in controlling the spread of bacteria in HIV/AIDS patients.

Macladin was developed in Japanese labs in the 1970s. It was a byproduct of a different version of erythromycin gone wrong. More than a decade later, an American company, Abbott Laboratories, created a partnership with the original manufacturer of Macladin, Taisho, to gain its international rights. In 2004, the medication became a generic brand in Europe and in the United States the following year.

Macladin is usually taken by mouth as a pill and oral suspension. There are also gel and lotion versions of the medication, created for topical use. Macladin is effective in preventing bacteria from growing and from spreading. It has antimicrobial effects similar to erythromycin but is far more effective and safe. Macladin, especially the pill and liquid form, will not cause discomfort if taken on an empty stomach. It is easily absorbed by the body and distributed into the site of infection. When using the oral suppression pills, it is best that the medication be taken with food.

A missed dose should be taken immediately. However, if the realization is too close to your next scheduled dose, skip the missed dose and continue with your normal schedule. Never take a double dose of Macladin and do not stop your intake of the medicine prematurely. Some symptoms may stop before the bacteria are killed. Since your goal is to kill the bacteria and stop it from spreading, you need to take it for the advised period of time. Following your doctor's prescription is important to keep you safe.

Like any strong medication, Macladin has some side effects. Diarrhea, vomiting, and swelling on the face are common reactions towards this medication. Some side effects could be severe and may include headache, motion sickness, skin rashes, xerostomia, anxiety attacks, hallucinations, yellowish skin, and kidney failure. If you experience any of these, rush to your doctor immediately. Any side effect that does not appear normal or is causing you discomfort should be a cause for alarm and you should consult your doctor immediately.

Special precautions should be taken by those with histories of allergies, asthma, hives, liver disease, kidney ailment, heart problem, or electrolyte imbalance. Macladin is not recommended for patients with these conditions as the reaction may be severe or life threatening. When taking a prescription medicine like this, your doctor's advice is always necessary. They will determine whether the medication is appropriate for you or not and will regulate your intake to ensure that no damage is done.

Macladin has the following structural formula:

Chemical structure of macladin


• Molecular formula of macladin is C38H69NO13
• Chemical IUPAC Name is 6-(4-dimethylamino-3-hydroxy-6-methyl-tetrahydropyran-2-yl)oxy- 14-ethyl-12,13-dihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl)oxy-7- methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• Molecular weight is 747.953 g/mol
Macladin available : 125mg/5ml suspension 100ml bottle, 250mg/5ml suspension 100ml bottle, 125mg/5ml suspension 50ml bottle, 250mg/5ml suspension 50ml bottle, 250mg tablets, 500mg tablets

Generic name: Clarithromycin

Brand name(s): Biaxin, Clarithromycine, Clathromycin, Klacid, Klaricid, Naxy, Prevpac, Veclam, Zeclar

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