Meridia is a brand name for sibutramine hydrochloride monohydrate, which is prescribed for the treatment of obesity. It aids in both weight loss and the maintenance of weight loss, and is recommended for use with a reduced calorie diet. Meridia is taken in 10mg doses once a day, though sometimes those who do not tolerate it well may take only 5g, and those who are resistant to weight loss may take 15g.
The most common side effects of Meridia can include dry mouth, loss of appetite, insomnia, constipation, and headache. Other more rare side effects, found in very few people, include fever, diarrhea, flatulence, dental problems, increased or decreased libido, tremors, hair loss, inflammation of the stomach, seizures, swelling, arthritis, agitation, leg cramps, depression, suicidal thoughts, confused thought processes, troubled dreams, nasal congestion, bronchitis, difficulty breathing, itchy skin, high or low blood pressure, loss of vision in one eye, and menstrual irregularities. If you have an allergic reaction to Meridia, you may experience hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
Meridia is a controlled substance classified in Schedule IV of the Controlled Substances Act. If you have a history of drug abuse, you may be monitored by your physician for signs of misuse of Meridian, such as development of tolerance or increasing of doses. It is important to remember that selling your Meridia is against the law. Meridia can also increase blood pressure significantly in some people, so your doctor may want to monitor you for changes in blood pressure and pulse rate.
Meridia should not be taken by people who are taking MAOIs, or monoamine oxidase inhibitors. If you are sensitive or allergic to any of the ingredients in Meridia, or if you have a serious eating disorder, you should not take Meridia. It is also not recommended for people who are already taking some other kind of medication for weight loss. Other medications that may affect the way Meridia works include medicines for coughs, colds, migraines, depression, or pain, or medications that contain narcotics, lithium, tryptophan, or antibiotics.
Meridia is in Pregnancy Category C, which means it has not been determined to be safe for pregnant women or their babies. It has been shown to produce abnormalities in animal studies, but has not been tested on human subjects. It is not recommended that you take Meridia if you are pregnant or planning to become pregnant, and if you could become pregnant, you should employ reliable birth control. It is not known whether Meridia is passed into breast milk; therefore it is not recommended for nursing mothers. Meridia has not been adequately tested for use in children, but it is expected that psychiatric side effects could be increased in this age group. For this reason, Meridia is not recommended for pediatric use. If you are over age sixty-five, you may be able to take Meridia, but you should be aware that you are at increased risk of decreased liver, kidney or heart functions.
Meridia has the following structural formula:
• Molecular formula of meridia is C17H26ClN
• Chemical IUPAC Name is 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-butan-1-amine
• Molecular weight is 279.848 g/mol
• Meridia available : 5mg capsules, 10mg capsules, 15mg capsules
Generic name: Sibutramine
Brand name(s): Medaria, Obestat, Reductil, Sibutramina, Sibutraminum
Review published on: 30 January 2008
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