Mertiran review

Mertiran, an imidazole antithyroid agent, converts to methimazole after being absorbed by the body, which generates an antithyroid action that works against hyperthyroidism (excessive production of thyroid hormones) and thyrotoxicosis (inflammation of the thyroid gland).

Mertiran is available as various brand names, including Atirozidina, CG1, Neo-Mercazole, Neo-Theyreostat, Neo-Tireol, Neomercazole and Tyrazol. This medicament is most often used for hyperthyroidism, when preparing a patient for thyroidectomy (surgical removal of all or part of the thyroid gland), and together with radio-iodine therapy in cases of hyperthyroidism.

Hyperthyroidism occurs when the thyroid gland produces an excess amount of T3 (triiosdothyronine) or T4 (thyroxine) hormones. Thyroid hormones regulate metabolism, so too many thyroid hormones in the body will speed up metabolism, including the digestion and cardiovascular functions. Symptoms of this include palpitations, intolerance for heat, insomnia, breathing difficulties, frequent bowel movement, fatigue, weight loss, warm moist skin, muscle weakness, hair loss, trembling hands, and light or absent menstrual periods.

Iodine is a main element in the formation of thyroid hormones. Mertiran works by preventing iodine from binding with other components to form thyroid hormones. This decreases thyroid function by reducing the thyroid gland's production of thyroid hormones. The effects of Mertiran are usually noticed three to four weeks after treatment begins, because the body will need to use up the thyroid hormones already existing before the medicament was started.

Patients with hyperthyroidism need to tell their healthcare professional if they are allergic to Mertiran or any of its ingredients. If patients experience any allergic reactions during treatment, the medicament should be stopped until they can consult their healthcare professional. Patients who are pregnant should use Mertiran with extreme caution and only if the benefits of taking the medicament outweigh the risks to the unborn child. Since Mertiran passes into breast milk, breastfeeding is not recommended while taking this medicament since it might harm the nursing infant.

Patients taking Mertiran may experience side effects including headaches, pruritus (itching), nausea, blood disorders, diarrhea, costiveness, nausea, emesis and stomach aches, myalgia (muscle pain), arthralgia (joint pain), jaundice (yellowing of the skin), hair loss, and a skin rash.

A serious side effect is a decrease in the bone marrow's production of blood cells, also known as bone marrow suppression. If this is accompanied by signs of an infection including a fever, a sore throat or mouth ulcers, the condition is serious and requires immediate medical attention.

If other side effects that are not listed here develop, consult your healthcare professional immediately.

Mertiran is available in pink, circular 20 and 5 mg. pills. Healthcare professionals often prescribe a gradually reduced dosage, giving just enough medicament to control the condition. Higher dosages may result in an enlargement of the thyroid gland.

Mertiran has the following structural formula:

Chemical structure of mertiran

• Molecular formula of mertiran is C7H10N2O2S
• Chemical IUPAC Name is ethyl 3-methyl-2-sulfanylideneimidazole-1-carboxylate
• Molecular weight is 186.2315 g/mol
Mertiran available : 20mg tablets

Generic name: Carbimazole

Brand name(s): Athyromazole, Atirozidina, Basolest, Carbethoxymethimazole, Carbimazol, Carbimazol Spofa, Carbimazolum, Carbotiroid, Neo-Mercazole, Neo-Thyreostat, Neo-Tireol, Neomercazole, Tyrazol

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