Metronidazole review

Metronidazole, sometimes spelled Metranidazol, is the generic name of a class of antibiotics that are used to treat bacterial and parasitic infections of the abdomen, skin and tissue, bones and joints, infections of the respiratory tract, and gynecological infections. It works by killing the bacteria that causes the infection by selectively blocking the biological functions of the invading bacterial cells, causing them to die off.

Metronidazole is a pro-drug, which means that its components must be activated in order for it to work. Metronidazole remains inactive until it is administered, then it metabolizes inside the body to target the organism it was meant to counteract. This type of drug design lessens the chances of Metronidazole attacking healthy cells, and improves absorption of the drug into the body.

Metronidazole is effective against anaerobic bacteria, single-celled organisms that can live in environments with very little oxygen. Some examples of infections caused by anaerobic bacteria include bacterial peritonitis, a disease of the abdomen; liver abscess, and abscesses of the Fallopian tubes and ovaries. Metronidazole is also used to treat intestinal parasites like Giardia lamblia and amoeba, which cause amoebic dysentery (a colon infection which can bring about bloody diarrhea), and vaginitis (a vaginal inflammation caused by the Trichomonas parasite).

Metronidazole is the generic name of several brands of medication. The most common of these brands are Flagyl and Protostat. There is even a Metronidazole treatment for the skin, topical MetroGel, which is used to remedy acne rosacea (a skin infection characterized by redness and pimples), and a Metronidazole-based vaginal gel for the treatment of bacterial vaginosis (a pregnancy-related or sexually transmitted disease caused by harmful bacteria).

When your doctor gives you a prescription for Metronidazole, it is recommended that you consume the prescribed dosage according to instructions, even if you start to experience relief from your symptoms. The reason for this lies in the fact that traces of the infection may still remain in your body and only a complete treatment will totally eradicate the bacteria and prevent it from returning.

Although Metronidazole is relatively safe to take when you are trying to fight off an infection, the drug does have accompanying contraindications and side-effects. Alcohol should be avoided when taking Metronidazole. A combination of the two can cause flushing, palpitations, nausea and vomiting. Some cold and cough medicines can also contain alcohol, so avoid these as well.

Inform your doctor if you have a liver disease like hepatitis, a stomach or intestinal disorder, or if you suffer from epilepsy or other forms of seizures before taking Metronidazole. These types of conditions may require a lower dosage or constant monitoring while you are undergoing treatment.

While Metronidazole is unlikely to harm the fetus during pregnancy, do not neglect to tell your doctor if you are pregnant. Traces of the drug may also pass into breast milk, so it is best to inform your doctor if you are breastfeeding.

Some unpleasant but tolerable side effects of Metronidazole include dark urine, nausea or vomiting, loss of appetite, a metallic taste in the mouth, constipation or minor diarrhea, headaches, or a sore tongue. However, if you experience any swelling in your face or mouth, difficulty in breathing, seizures, numbness or tingling, dizziness, or diarrhea, stop taking Metronidazole at once. These are symptoms of an allergy to the medication and you should seek emergency medical attention as soon as possible.

Let your doctor know if you are taking other medications that contain barbiturates, warfarin, phenytoin, and lithium, as combinations of these drugs and Metronidazole may cause dangerous side effects.

As with all other medications, your Metronidazole prescription should not be shared with anyone. It should be stored away from moisture and sunlight, and not be left where children can find them.

Metronidazole has the following structural formula:

Chemical structure of metronidazole

• Molecular formula of metronidazole is C6H9N3O3
• Chemical IUPAC Name is 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol
• Molecular weight is 171.154 g/mol
Metronidazole available : 250mg tablets, 500mg tablets

Brand name(s): Acromona, Anagiardil, Arilin, Atrivyl, Benzoylmetronildazole, Bexon, Clont, Cont, Danizol, Deflamon, Efloran, Elyzol, Entizol, Eumin, Flagemona, Flagesol, Flagil, Flagyl, Flegyl, Fossyol, Giatricol, Gineflavir, Helidac, Klion, Klont, Meronidal, Methronidazole, Metrogel, Metrolag, Metrolotion, Metrolyl, Metromidol, Metronidaz, Metronidazol, Metronidazolo, Metrotop, Mexibol, Monagyl, Monasin, Nalox, Neo-Tric, Nida, Nidagel, Noritate, Novonidazol, Orvagil, Protostat, Rathimed, Sanatrichom, Satric, Takimetol, Trichazol, Trichex, Trichocide, Trichomol, Trichopal, Trichopol, Tricocet, Tricom, Trikacide, Trikamon, Trikojol, Trikozol, Trimeks, Trivazol, Vagilen, Vagimid, Vertisal, Wagitran, Zadstat

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