Mielevcin is a common
cancer medicament known to slow down the neoplastic activity of malignant cells. It is a generic and non-specific cell type alkylating antineoplastic agent that was initially created as a therapeutic medicament for chronic myeloid
leukemia and has been reclassified as a generic medicament for cancer cells.
This medicament controls the burden of tumor formation and significantly slows down metastasis of cancer cells to other regions of the body. It is not able to entirely impede the progress of the cancer cells, as it is incapable of reversing the overall cellular aberration effects of the cancer cells. Cytogenic abnormalities still progress, but at a much slower rate than without the medicament.
Mielevcin is for cancer patients susceptible to chemotherapy and medicament induction therapy. The medicament works on a cellular level by producing Guanine-guanine strands of genetic output as it attacks the carbon strand in the mesylate group in a malignant cancer cell. This has large success rates and results in an apoptotic state. The result may decrease overall strength as massive cellular destruction on the target area is occurring, which is evidenced by destruction of normal cells, especially in
bone marrows.
Mielevcin is an alternative for non-operative stem cell transplantation, therefore increasing the patient's receptivity for an oncoming transplant of stem cells.
Cancer patients should have all of the proper information regarding the medicament and the proper supervision and expertise of a qualified physician.
Mielevcin is a palliative medicament given in dosages of 60 micrograms per body weight in kilos, with a maximum of 4 milligrams per day. For treatment of Polycythemia vera, 4 to 6 milligrams is recommended per day over 4 to 6 weeks. For thrombocythaemia, 2 to 4 milligrams per day is suggested. Conditioning therapeutic medicament plans suggest about 3.5 to 4 milligram per body weight in kilos per day, given in four dosages, totaling 14 to 16 milligrams per kilo body weight.
Side effects may include general toxicity leading to fibrosis in the pulmonary tract, seizures, wasting of the muscles and organs, and cases of
liver malfunction and failure. For seizures,
phenytoin may be used to lessen the occurrence.
Talk with your physician about any medications already being used to determine possible medicament-to-medicament interactions. Special consideration should be given to antifungal medications such as azole variants. This medicament is contraindicated with phenothiazines and other cancer medications such as
cyclosporine. If contraindications of medicament is suspected, take medicament cautiously three days after last previous medicament is used.
Acetaminophen is not to be used in conjunction with Mielevcin since it raises
blood levels and may increase the risk of complicated
high blood pressure.
Mielevcin has the following structural formula:
• Molecular formula of mielevcin is C6H14O6S2
• Chemical IUPAC Name is 1,4-bis(methylsulfonyloxy)butane
• Molecular weight is 246.304 g/mol