Minocycline review

Minocycline hydrochloride, or Minocycline, is a bacteriostatic antibiotic that belongs to a class of broad spectrum medications known as tetracycline antibiotics. It is commonly prescribed for the treatment of pneumonia and other infections affecting the respiratory tract.

Minocycline is also indicated for skin infections and infections of the genital, urinary and rectal tract. It is likewise effective in treating acne, and in eradicating bacteria that may lead to meningitis, a dangerous infection characterized by the swelling of the tissues surrounding the brain.

Minocyline works by preventing bacteria from growing and spreading throughout the body. Other bacterial infections treated by this medication include gonorrhea, anthrax, tick fever, cholera, amoebic dysentery, syphilis, lyme disease, chlamydia, Rocky Mountain spotted fever, and infections caused by the drug-resistant bacteria, Acinetobacter.

Before taking this drug, patients should inform their doctor if they are allergic to Minocycline, doxycyline, tetracycline or other similar medications. To rule out the possibility of adverse drug interactions, the patient should also let their doctor know of any over-the-counter or prescription medicines they are taking, including any vitamin, mineral or herbal supplements. This information will be helpful in determining whether the doctor will need to adjust the patient's Minocycline dosage or subject the patient to special medical observation for the duration of the therapy.

Patients currently taking hormonal contraceptives will find that Minocycline may decrease the effectiveness of their contraceptive medication. They should consult their doctor for other methods of contraception while undergoing Minocycline treatment. Conversely, antacids, iron and calcium supplements, and magnesium-based laxatives can render Minocycline less effective. Patients should make sure that they do not take these medications within 3 hours of taking Minocyline.

Patients should also inform their doctor if they have diabetes, liver disease or kidney ailments so as to receive an adjusted dosage of the medication. As Minocycline can cause dizziness, patients under treatment should refrain from performing activities which require a high level of alertness, such as driving or operating machinery. Minocycline also causes photosensitivity, hence patients should apply sunscreen, and wear protective clothing and sunglasses whenever they go outdoors.

Minocycline has been classified by the FDA as Pregnancy Category D, meaning it is potentially harmful to the unborn child. For this reason, patients who are pregnant should avoid taking Minocycline. Likewise, patients should not take this medication while they are breastfeeding. Minocycline can be excreted into breast milk and can harm the nursing infant's bones and teeth. Minocycline should not be administered to children younger than 8 years of age either, as it may affect their growth and permanently stain their teeth.

Other side effects caused by Minocyline include mild nausea, dizziness, stomach upset or diarrhea, loss of coordination, headaches, drowsiness, and vomiting. It can also cause itching in the vaginal or rectal area, sunburn, mild hearing loss or ringing in the ears, and changes in skin color.

Minocycline is available under several brand names including Myrac, Dynacin, Minocin, Sebomin, Mino-Tabs, Solodyn, Arestin, Akamin, Minoderm, Aknemin and Minomycin. Dosage will depend on a patient's condition and may be taken in capsule or tablet form from two to up to four times a day on an empty stomach.

Minocylcine should be taken according to the entire period of time prescribed by the doctor. Patients should remember that while symptoms of their condition may disappear, the infection may not be entirely eradicated until they complete their prescribed dosage.

Minocycline has the following structural formula:

Chemical structure of minocycline

• Molecular formula of minocycline is C23H27N3O7
• Chemical IUPAC Name is (2E,4S,4aR,5aS,12aR)-2-(amino-hydroxy-methylidene)-4,7-bis(dimethylamino)- 10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
• Molecular weight is 457.477 g/mol
Minocycline available : 50mg capsules, 75mg capsules, 100mg capsules, 75mg tablets

Brand name(s): Arestin, Dynacin, Klinomycin, Minociclina, Minocin, Minocyclin, Minocyclinum, Minocyn, Minomycin, Vectrin

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