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Myotonine chloride

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Myotonine chloride

Myotonine chloride review





Myotonine Chloride, a parasympathomimetic choline ester with a stimulating effect on muscarinic receptors, is responsible for the contraction of the smooth muscle tone. It is often given to patients who have recently had abdominal surgery, given birth, or who suffer from urinary retention to help them empty their bladder. Myotonine Chloride is suggested for oral or subcutaneous (under the skin) administration to ease urinary retention due to general anesthesia in surgery, diabetic neuropathy of the bladder (a diabetes complication that causes nerve damage), in the management of gastrointestinal atony (lack of gastric muscular tone), and bladder overdistention (the bladder retains an abnormal amount of residual urine).

Myotonine Chloride can be used to treat urination problems due to a malfunction of the bladder's nerves or weak bladder muscles, if there has been no prior diagnosis of urinary blockage. It is also given to patients with digestive problems like gastroesophageal reflux (heartburn).

Myotonine Chloride stimulates the muscarinic receptors in the bladder and gastrointestinal tract, which causes them to contract and expel urine, and improve gastrointestinal motility, increase gastric tone and restore peristalsis, the regular contraction of smooth muscles, which moves the contents of the digestive tract on.

Patients need to disclose their complete medical history to their physician, including whether or not the patient has or has had stomach ulcers, uncontrolled hyperthyroidism (overactive thyroid), asthma, recent bladder or intestinal surgery, intestinal blockage or bowel disease, slow heart rate or low blood pressure, coronary artery disease, difficult urination, Parkinson's disease, or any kind of seizure disorder like epilepsy. Patients with any of these conditions should not take Myotonine Chloride, or at the very least, their physician should prescribe a lower dosage and monitor them throughout the course of treatment.

Patients should tell their physician if they have had allergic reactions to Myotonine Chloride, tartrazine dye, food preservatives or any other medicines. Patients should also let their physician know if they are pregnant or plan to become pregnant. Myotonine Chloride has been categorized by the Food & Drug Administration as pregnancy category C, so it is unknown if the medication poses harm to an unborn baby. Breastfeeding mothers should talk to their physicians before taking Myotonine Chloride to determine the risks to the nursing baby, if any.

Other medicaments may interact negatively with Myotonine Chloride so patients taking quinidine, donezipil, tacrine, procainamide, cholinesterase inhibitors, ganglionic blocking compounds, and medicaments used for colds or nasal congestion may experience negative reactions when taking these medicaments with Myotonine Chloride. Patients should provide their physician a list of all prescription and non-prescription medicaments they are taking, including vitamins, minerals and herbal supplements prior to taking Myotonine Chloride.

This medication can cause drowsiness so patients taking this medication should refrain from driving or operating any type of machinery. Since alcoholic beverages contribute to the dizziness caused by this medication, patients taking this medication should refrain from consuming alcoholic beverages. Myotonine Chloride may alter some blood test results. Due to this, patients are advised to inform their physician that they are taking this medication before undergoing any blood tests.

Side effects include upset stomach, increased salivation, nausea, vomiting, sweating or flushing. If the patient experiences shortness of breath, a slow heart rate, hypotension (low blood pressure), bronchial spasms or fainting, call their physician immediately. If there are extreme allergic reactions such as swelling of the lips, tongue or face, hives, closing of the throat, wheezing and tightness in the chest, seek emergency medical attention.

This medication is available under the brand names Duvoid by Roberts, Myotonachol by Glenwood, and Urecholine by Merck Frosst, which manufacture the medication in 5mg round white tablets, 10mg round pink tablets, 25mg round yellow tablets and 50mg round yellow tablets.

Proper dosage of the medication is dependant on the patient and the type of illness being treated. Patients should take the medication orally on an empty stomach with plenty of fluids as prescribed by their physician.

Myotonine chloride has the following structural formula:

Chemical structure of myotonine chloride


• Molecular formula of myotonine chloride is C7H17N2O2+
• Chemical IUPAC Name is 2-carbamoyloxypropyl-trimethylazanium
• Molecular weight is 161.2221 g/mol
Myotonine chloride available : 5mg tablets, 10mg tablets, 25mg tablets, 50mg tablets

Generic name: Bethanechol

Brand name(s): Besacholine, Duvoid, Mechotane, Mechothane, Mecothane, Mictone, Mictrol, Myocholine, Myotonachol, Myotonine chloride, Urabeth, Urecholine, Urecholine Chloride, Uro-Carb

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