is the brand name for the generic drug nimodipidine. It is used to improve symptoms caused by the spasms that are the result of ruptured blood vessels
in the brain
, causing bleeding between the brain and the skull
. It is a calcium
channel blocker, meaning that its function is to relax the blood
vessels by preventing the flow of calcium into the vessel, and is given every four hours when blood vessels first rupture. Nimotop has also been used in the treatment of migraine headaches
Nimotop comes in capsules, but if you can’t swallow them, the liquid inside the capsules can be administered through a feeding tube. Nimotop should never be given through an IV, that is, intravenously. If you can’t swallow the capsules, it should only be given through a GI (gastrointenstinal) tube. For patients who cannot swallow, the manufacturer has also made an orally administered liquid, so that there is no confusion
between IV and GI administration; these kinds of errors can lead to serious complications or death.
Side effects of Nimotop can include nausea
, and flushing, especially in the first few days, while your body is acclimating to the presence of the drug in your system. You may also experience depression
, mood swings, a rash or hives
in your hands or feet, fainting, unusual weakness, unusually fast or slow heart
rate, difficulty breathing, wheezing, muscle cramps, or bruising or bleeding. If any of these occur you should contact your doctor. You may be having an allergic reaction if you have an unusually fast or slow heart rate, fainting or severe dizziness
, hives, or swelling of the face, lips
or throat. If you have any of these allergic symptoms, stop taking Nimotop and call your doctor immediately.
It is not known whether Nimotop is safe for pregnant women or their babies, but animal studies have suggested that it can be quite harmful to a developing fetus. Therefore, Nimotop should only be given if the necessity for the woman outweighs the possible risks to the baby. It is also not known whether Nimotop appears in breast
milk, so it is not recommended that you continue breast feeding while taking Nimotop.
There are other precautions that should be taken during treatment with Nimotop. You should always inform your doctor if you are taking any other medications, including non-prescription medications. You should not take Nimotop of you have a history of low blood pressure, liver
disease, high blood pressure
, or a history of heart problems, including a slow heart rate, congestive heart failure
, or heart attacks, or if you are taking intravenous calcium. In addition, you should avoid drinking grapefruit juice while you are taking Nimotop.
There have been no studies on whether Nimotop is safe for children, so it is not recommended for pediatric use. It is also unknown whether geriatric patients respond differently to Nimotop than younger ones, but studies have shown that those over age 65 are more likely to experience severe side effects.
Nimotop has the following structural formula:
• Molecular formula of nimotop is C21H26N2O7
• Chemical IUPAC Name is 2-methoxyethyl1-methylethyl2,6-dimethyl-4-(3-nitrophenyl)- 1,4-dihydropyridine-3,5-dicarboxylate
• Molecular weight is 418.44 g/mol
• Nimotop available : 30mg capsules