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Nitazoxanide

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Nitazoxanide

Nitazoxanide review





Nitazoxanide, which is known in various trade names like Annita, Alinia, Paramix, Pacovanton, Kidonax, Dexidex, Daxon, Nitazox, Nitax, Zox, and so forth, is both an anti-protozoal agent and a manmade nitrothiazolyl-salicylamide offshoot. The medication itself comes in a pale yellow crystalline powder form that's barely soluble in ethanol and is nigh-insoluble in water.

This medication of many brand names is the first-line option for Giardia lambia infection or Cryptosporidium parvum therapy in immunocompetent children and adults. It's also a viable second or third option for infectious diarrhea treatment, particularly diarrhea caused by the abovementioned Giardia lamblia and Cryptosporidium parvum in patients a year of age and older. Nitazoxanide is also in the second phase of clinical trials that are testing to see if it could treat Hepatitis C alongside ribavirin and peginterferon alfa-2a.

The daily recommended dose for this drug is a three-day, twice-daily (that is, every twelve hours) oral administration with food or as instructed by your physician. Children eleven years and up can take these tablets, but those below that range cannot. Children less than eleven years of age should be treated with the nitazoxanide suspension. Moreover, antibiotics are most effective when the amount of medication in your body is maintained at an even rate and level. As such, patients should make sure to never miss out a dose and take nitozoxanide at uniformly spaced intervals.

You shouldn't stop taking this drug once symptoms have ceased after just a few doses either; you must instead take its full-prescribed amount till it has been completely consumed. Ceasing your therapy prematurely could cause the parasites and other bad germs in your body to spread and worsen, which may result in a relapsed infection. If symptoms of your disease persist or don't improve in the least, consult a medical professional for further assistance.

Non-allergenic-related nitazoxanide side effects are mostly gastrointestinal in nature, which can include diarrhea, nausea, headache, vomiting, and abdominal pain. Clinical trials conducted on the drug have reported that no grave or dangerous events have occurred from using the medication, and this was further confirmed by the prescription information of the drug's parent company.

Actual allergy to the medication is unlikely, but in case it does happen, you must seek immediate medical attention. To wit, symptoms of a critical allergic reaction may include difficulty in breathing, severe dizziness, swelling, itchiness, and rash. If you notice any other side effects not included in this article, then contact your pharmacist and doctor as soon as possible in order to report your case.

Before undergoing nitazoxanide therapy, report to your pharmacist or doctor if you are among the relative few who are allergic to the drug, or if you have any other allergies from other medications and various substances. You should also disclose your complete medical history to your healthcare attendant, especially if you've ever had a weak immune system (e.g., an HIV infection), kidney disease, or liver disease.

While in the middle of treatment, you must not take over-the-counter medications to treat diarrhea without first asking your pharmacist or doctor if it's okay to do so. Pregnant mothers should also tell their physician about their condition before taking this drug. At this point in time, it's still unknown whether or not nitazoxanide passes into breast milk, so it's again prudent to consult your doctor first before attempting to breastfeed.

Nitazoxanide has the following structural formula:

Chemical structure of nitazoxanide


• Molecular formula of nitazoxanide is C12H9N3O5S
• Chemical IUPAC Name is [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate
• Molecular weight is 307.283 g/mol
Nitazoxanide available : 500mg tablets

Brand name(s): Alinia, Nitazoxanid, Nitazoxanida, Nitazoxanidum, Tizoxanide Glucuronide

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